SCHEMBL4082011

SCHEMBL4082011

NCCCC(CO)(CO)CCCN

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 3/20 0.39
PDE3A Q14432 1/20 0.39
NFKB1 P19838 1/20 0.35
ODC1 P11926 2/20 0.34
TSHR P16473 4/20 0.33
ALDH1A1 P00352 3/20 0.33
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA3 P07451 2/20 0.33
CA4 P22748 2/20 0.33
CA6 P23280 2/20 0.33
CA5A P35218 2/20 0.33
CA7 P43166 2/20 0.33
CA9 Q16790 2/20 0.33
CA14 Q9ULX7 2/20 0.33
CA5B Q9Y2D0 2/20 0.33
LMNA P02545 2/20 0.33
BLM P54132 2/20 0.33
DNM1 Q05193 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14655732 0.94 FDPS (0.39) FDPSPDE3ANFKB1ODC1TSHR
SCHEMBL13434821 0.94 FDPS (0.39) FDPSPDE3ANFKB1ODC1TSHR
SCHEMBL8844877 0.89 FDPS (0.33) FDPSPDE3AODC1
SCHEMBL2362566 0.85 NFKB1 (0.41) FDPSPDE3ANFKB1TSHRALDH1A1
Hydrochloric Acid SCHEMBL7207058 0.82 FDPS (0.39) FDPSPDE3ANFKB1TSHRALDH1A1
SCHEMBL19620158 0.82 DNM1 (0.36) FDPSPDE3ATSHRALDH1A1DNM1
SCHEMBL15800756 0.80 ALDH1A1 (0.35) TSHRALDH1A1
SCHEMBL18694932 0.79 NFKB1 (0.46) FDPSPDE3ANFKB1ODC1TSHR
SCHEMBL6472790 0.79 TSHR (0.39) FDPSPDE3ANFKB1ODC1TSHR
SCHEMBL5607589 0.78 DNM1 (0.39) FDPSTSHRALDH1A1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243540-A1 PROBE RELATED REAGENTS AND METHODS BRENTANO BIOTECHNOLOGY ASSOCIATES (US) 2025-07-31 US disclosed
CN-115942939-A Diastereomer ligation reagents for nucleotide probes 布伦塔诺生物技术联合公司 2023-04-07 CN disclosed
EP-4034131-A1 DIASTEREOMERIC LINKING REAGENTS FOR NUCLEOTIDE PROBES Brentano Biotechnology Associates (US) 2022-08-03 EP disclosed
US-20220073546-A1 DIASTEREOMERIC LINKING REAGENTS FOR NUCLEOTIDE PROBES BRENTANO BIOTECHNOLOGY ASSOCIATES (US) 2022-03-10 US disclosed
WO-2021061154-A1 DIASTEREOMERIC LINKING REAGENTS FOR NUCLEOTIDE PROBES BRENTANO BIOTECHNOLOGY ASSOCIATES (US) 2021-04-01 WO disclosed
US-7560231-B2 Mannitol and glucitol derivatives ROCHE MOLECULAR SYSTEMS, INC. (US) 2009-07-14 US disclosed
EP-1431298-B1 Mannitol and glucitol derivatives ROCHE DIAGNOSTICS GMBH (DE) 2006-03-08 EP disclosed
US-20040157247-A1 Mannitol and glucitol derivatives ROCHE MOLECULAR SYSTEMS, INC (US) 2004-08-12 US disclosed
EP-1431298-A1 Mannitol and glucitol derivatives Roche Diagnostics GmbH (DE) 2004-06-23 EP disclosed
EP-1431297-A1 Mannitol and glucitol derivatives BOEHRINGER MANNHEIM GMBH (DE) 2004-06-23 EP disclosed
US-6031091-A WITH PROTECTING GROUPS WHICH MAY BE REMOVED FOR COUPLING TO ANOTHER NUCLEOTIDE; FOR HYBRIDIZATION PROBES WITH ENHANCED SENSITIVITY GEN-PROBE INCORPORATED (US) 2000-02-29 US disclosed
US-5696251-A OLIGONUCLEOTIDES GEN-PROBE INCORPORATED (US) 1997-12-09 US disclosed
US-5656744-A COMPLEXING GEN-PROBE INCORPORATED (US) 1997-08-12 US disclosed
US-5585481-A VERSATILITY; NON-NUCLEOTIDE MONOMERIC UNIT HAVING A LIGAND AND FIRST AND SECOND COUPLING GROUPS WHICH ARE LINKED TO THE NON-NUCLEOTIDE MONOMERIC UNIT ; LABELS, INTERCALATORS, PROBES GEN-PROBE INCORPORATED (US) 1996-12-17 US disclosed
EP-0313219-B1 Non-nucleotide linking reagents for nucleotide probes GEN PROBE INC (US) 1996-05-08 EP disclosed
EP-0313219-A2 Non-nucleotide linking reagents for nucleotide probes GEN-PROBE INCORPORATED (US) 1989-04-26 EP disclosed
WO-1989002439-A1 NON-NUCLEOTIDE LINKING REAGENTS FOR NUCLEOTIDE PROBES ML TECHNOLOGY VENTURES, L.P. (US) 1989-03-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040157247-A1 Mannitol and glucitol derivatives ALDOA, DERA, SORD FDPS 2578/4885PDE3A 4386/4885NFKB1 2433/4885
US-20250243540-A1 PROBE RELATED REAGENTS AND METHODS DNTT, NCL, NT5C3B FDPS 636/4885PDE3A 4528/4885NFKB1 3585/4885
US-20220073546-A1 DIASTEREOMERIC LINKING REAGENTS FOR NUCLEOTIDE PROBES NCL, PCNA, DNTT FDPS 447/4885PDE3A 4206/4885NFKB1 3076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.