Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569129 | 0.89 | ALDH1A1 (0.62) | ALDH1A1BDKRB1MAPTLMNAPDK1 | |
| SCHEMBL8569299 | 0.82 | MAPT (0.67) | ALDH1A1MAPTLMNACYP2C9CYP1A2 | |
| SCHEMBL6357109 | 0.81 | PDK1 (0.72) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL16109601 | 0.77 | RXFP1 (0.48) | NR4A1ALDH1A1BDKRB1MAPTLMNA | |
| SCHEMBL3444656 | 0.76 | NR4A1 (0.84) | NR4A1ALDH1A1MAPTCYP2C9NPSR1 | |
| SCHEMBL6510419 | 0.76 | PDK1 (0.62) | ALDH1A1MAPTLMNAPDK1PDK2 | |
| SCHEMBL29380114 | 0.75 | ALDH1A1 (0.61) | NR4A1ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL10413044 | 0.75 | RAB9A (0.67) | ALDH1A1MAPTLMNANPSR1L3MBTL1 | |
| SCHEMBL6169653 | 0.74 | MEN1 (0.56) | ALDH1A1LMNACYP1A2CYP2C19MEN1 | |
| SCHEMBL29118239 | 0.73 | ALDH1A1 (0.58) | ALDH1A1BDKRB1MAPTPDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090062317-A1 | MEDICINAL USE OF RECEPTOR LIGANDS | 7TM PHARMA A/S (DK) | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062317-A1 | MEDICINAL USE OF RECEPTOR LIGANDS | MCHR1, MCHR2, MC1R | NR4A1 267/4885ALDH1A1 1058/4885BDKRB1 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.