Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.68 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | CD44 | P16070 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TDP2 | O95551 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29903130 | 1.00 | ALDH1A1 (0.68) | ALDH1A1CYP3A4TDP1TSHRCYP1A2 | |
| SCHEMBL10348247 | 0.85 | CD44 (0.81) | ALDH1A1CYP3A4TDP1TSHRCYP1A2 | |
| SCHEMBL30231905 | 0.84 | CYP1A2 (0.68) | ALDH1A1CYP3A4TDP1TSHRCYP1A2 | |
| SCHEMBL248677 | 0.84 | CYP1A2 (0.68) | ALDH1A1CYP3A4TDP1TSHRCYP1A2 | |
| SCHEMBL28494492 | 0.84 | CYP1A2 (0.68) | ALDH1A1CYP3A4TDP1TSHRCYP1A2 | |
| SCHEMBL30259992 | 0.83 | CYP3A4 (0.59) | ALDH1A1CYP3A4TDP1TSHRCYP1A2 | |
| SCHEMBL424167 | 0.83 | CYP1A2 (1.00) | ALDH1A1CYP3A4TDP1TSHRCYP1A2 | |
| SCHEMBL29365003 | 0.83 | ALDH1A1 (1.00) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 | |
| SCHEMBL29463284 | 0.83 | CYP1A2 (1.00) | ALDH1A1CYP3A4TDP1TSHRCYP1A2 | |
| SCHEMBL48843 | 0.83 | ALDH1A1 (1.00) | ALDH1A1CYP3A4TDP1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12083498-B2 | Chromatographic materials for the separation of unsaturated molecules | WATERS TECHNOLOGIES CORPORATION (US) | 2024-09-10 | — | — | US | disclosed |
| CN-115003677-B | Compounds having inhibitory activity against KRAS G12D mutations | 大鹏药品工业株式会社 | 2024-08-27 | — | — | CN | disclosed |
| WO-2024151024-A1 | COMPOUND FOR CAPPING LAYER AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | 주식회사 진웅산업 | 2024-07-18 | — | — | WO | disclosed |
| CN-111644164-B | Chromatographic material for separating unsaturated molecules | 沃特世科技公司 | 2024-03-08 | — | — | CN | disclosed |
| WO-2023226264-A1 | HYPERBRANCHED POLYPHENYL AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 苏州大学 | 2023-11-30 | — | — | WO | disclosed |
| US-20230381112-A1 | Compositions and Methods of Manufacturing Amphiphilic Block Copolymers that Form Nanoparticles in Situ | VACCITECH NORTH AMERICA, INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230381112-A1 | Compositions and Methods of Manufacturing Amphiphilic Block Copolymers that Form Nanoparticles in Situ | VACCITECH NORTH AMERICA, INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-20230348495-A1 | A COMPOUND HAVING INHIBITORY ACTIVITY AGAINST KRAS G12D MUTATION | ASTEX THERAPEUTICS LIMITED (GB) | 2023-11-02 | — | — | US | disclosed |
| WO-2023111919-A1 | OPTO-ELECTRONIC DEVICE COMPRISING A PATTERNING COATING COMPRISING A PLURALITY OF MATERIALS | OTI LUMIONICS INC. (CA) | 2023-06-22 | — | — | WO | disclosed |
| WO-2022266340-A1 | SELF-ASSEMBLING NANOPARTICLES BASED ON AMPHIPHILIC PEPTIDES FOR DRUG DELIVERY APPLICATIONS | VACCITECH NORTH AMERICA, INC. (US) | 2022-12-22 | — | — | WO | disclosed |
| US-20060281738-A1 | 2-Naphthylimino-1,3-thiazine derivative | SHIONOGI AND CO., LTD. (JP) | 2006-12-14 | — | — | US | disclosed |
| CN-1863784-A | 2-naphthylimino-1,3-thiazine derivative | SHIONOGI & CO (JP) | 2006-11-15 | — | — | CN | disclosed |
| EP-1669390-A1 | POLYAMINOPYRIDINES AND METHOD FOR PRODUCING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2006-06-14 | — | — | EP | disclosed |
| EP-1659117-A1 | 2-NAPHTHYLIMINO-1,3-THIAZINE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2006-05-24 | — | — | EP | disclosed |
| US-5047553-A | Tetrafluoro-N-phenylphthalimide | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-09-10 | — | — | US | disclosed |
| US-5001227-A | Fibre-reactive 1:1 chromium complex azo or azomethine dyes having a bidentate chelating group and a monofunctional neutral ligand | CIBA-GEIGY CORPORATION (US) | 1991-03-19 | — | — | US | disclosed |
| US-4990598-A | Colorfastness | CIBA-GEIGY CORPORATION, A CORP. OF NEW YORK | 1991-02-05 | — | — | US | disclosed |
| US-4960870-A | DYEING WOOL, POLYAMIDES; FIBER REACTIVE DYES | CIBA-GEIGY CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |
| US-4813972-A | USING LEVELING DYES, COLORFASTNESS | CIBA-GEIGY CORPORATION (US) | 1989-03-21 | — | — | US | disclosed |
| US-4723001-A | Fibre-reactive chromium complexes and their preparation and use | CIBA-GEIGY CORPORATION (US) | 1988-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281738-A1 | 2-Naphthylimino-1,3-thiazine derivative | NPM1, OXTR, CYP2S1 | ALDH1A1 1571/4885CYP3A4 95/4885TDP1 3815/4885 |
| US-20230348495-A1 | A COMPOUND HAVING INHIBITORY ACTIVITY AGAINST KRAS G12D MUTATION | KRAS, NRAS, HRAS | ALDH1A1 2932/4885CYP3A4 4491/4885TDP1 3471/4885 |
| US-12083498-B2 | Chromatographic materials for the separation of unsaturated molecules | C9, EPHX2, ALOX5 | ALDH1A1 1087/4885CYP3A4 511/4885TDP1 4724/4885 |
| US-20230381112-A1 | Compositions and Methods of Manufacturing Amphiphilic Block Copolymers that Form Nanoparticles in Situ | SBDS, MTDH, DLST | ALDH1A1 2783/4885CYP3A4 1359/4885TDP1 3783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.