Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | PYGM | P11217 | 2/20 | 0.32 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758299 | 0.76 | LMNA (0.42) | ALDH1A1KMT2ALMNAPYGMPYGL | |
| SCHEMBL4755316 | 0.71 | HCAR2 (0.36) | ALDH1A1KMT2ALMNAPYGMPYGL | |
| SCHEMBL4755372 | 0.68 | TSHR (0.39) | ALDH1A1KMT2ALMNAKDM4ETDP1 | |
| SCHEMBL3392997 | 0.64 | TDP1 (0.40) | ALDH1A1KMT2ALMNAKDM4EHPGD | |
| SCHEMBL584871 | 0.64 | RXFP1 (0.71) | PRNPRXFP1HSD11B1ALDH1A1KMT2A | |
| SCHEMBL29939764 | 0.64 | RXFP1 (0.71) | PRNPRXFP1HSD11B1ALDH1A1KMT2A | |
| SCHEMBL9025206 | 0.61 | ALDH1A1 (0.64) | PRNPRXFP1HSD11B1ALDH1A1KMT2A | |
| SCHEMBL29513035 | 0.61 | ALDH1A1 (0.64) | PRNPRXFP1HSD11B1ALDH1A1KMT2A | |
| SCHEMBL30693720 | 0.60 | PRNP (0.49) | PRNPRXFP1HSD11B1ALDH1A1KMT2A | |
| SCHEMBL13963145 | 0.60 | HSD11B1 (0.62) | PRNPRXFP1HSD11B1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009006580-A1 | OPTIONALLY CONDENSED DIHYDROPYRIDINE, DIHYDROPYRIMIDINE AND DIHYDROPYRANE DERIVATIVES ACTING AS LATE SODIUM CHANNEL BLOCKERS | CV THERAPEUTICS, INC. (US) | 2009-01-08 | — | — | WO | disclosed |