Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.58 |
| ▸ | CDK1 | P06493 | 3/20 | 0.58 |
| ▸ | CDK4 | P11802 | 3/20 | 0.58 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.58 |
| ▸ | CCND1 | P24385 | 3/20 | 0.58 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.58 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | BAD | Q92934 | 1/20 | 0.44 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9421099 | 1.00 | ALDH1A1 (0.65) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| Acrylic Acid SCHEMBL29184905 | 0.88 | TRPA1 (0.52) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| Biphenyl SCHEMBL4693704 | 0.87 | ALDH1A1 (0.86) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL9131419 | 0.85 | MAOB (0.64) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL31114357 | 0.83 | CDK4 (0.72) | ALDH1A1TRPA1LMNAALOX5MAPK1 | |
| SCHEMBL5889919 | 0.81 | CCNB2 (0.51) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL5889921 | 0.81 | CCNB2 (0.51) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL5889707 | 0.81 | CCNB2 (0.73) | ALDH1A1CCNB2CDK1CDK4CCNB1 | |
| SCHEMBL5889708 | 0.81 | CCNB2 (0.73) | ALDH1A1CCNB2CDK1CDK4CCNB1 | |
| SCHEMBL334479 | 0.81 | ALDH1A1 (0.74) | ALDH1A1TRPA1LMNAALOX5MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4709107-A | Process for producing nitrones | GENERAL ELECTRIC COMPANY (US) | 1987-11-24 | — | — | US | claimed |
| US-20150344407-A1 | FENDILINE DERIVATIVES AND METHODS OF USE THEREOF | AVIARA PHARMACEUTICALS, INC. | 2015-12-03 | — | — | US | disclosed |
| US-8877353-B2 | Platinum (II) tetradentate ONCN complexes for organic light-emitting diode applications | VERSITECH LIMITED (HK) | 2014-11-04 | — | — | US | disclosed |
| WO-2014031755-A1 | FENDILINE DERIVATIVES AND METHODS OF USE THEREOF | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-02-27 | — | — | WO | disclosed |
| US-20120018711-A1 | PLATINUM (II) TETRADENTATE ONCN COMPLEXES FOR ORGANIC LIGHT-EMITTING DIODE APPLICATIONS | THE UNIVERSITY OF HONG KONG (HK) | 2012-01-26 | — | — | US | disclosed |
| WO-2012009957-A1 | PLATINUM(II) TETRADENTATE O-N-C-N COMPLEXES FOR ORGANIC LIGHT-EMITTING DIODE APPLICATIONS | VERSITECH LIMITED (CN) | 2012-01-26 | — | — | WO | disclosed |
| EP-0892805-A1 | PRODUCTION OF 7-AMINOCEPHALOSPORANIC ACID DERIVATIVE | Takeda Chemical Industries, Ltd. (JP) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997039002-A1 | PRODUCTION OF 7-AMINOCEPHALOSPORANIC ACID DERIVATIVE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-23 | — | — | WO | disclosed |
| US-5332857-A | 3,5-dihydroxy-6,8-nonadienoic acids and derivatives as hypocholesterolemic agents | PFIZER INC. (US) | 1994-07-26 | — | — | US | disclosed |
| EP-0312269-B1 | 3,5-DIHYDROXY-6,8-NONADIENOIC ACIDS AND DERIVATIVES AS HYPOCHOLESTEROLEMIC AGENTS | PFIZER INC. (US) | 1993-06-16 | — | — | EP | disclosed |
| US-5151545-A | 3,5-DIHYDROXY-6,8-NONADIENOIC ACIDS AND DERIVATIVES AS HYPOCHOLESTEROLEMIC AGENTS | PFIZER INC. (US) | 1992-09-29 | — | — | US | disclosed |
| WO-1989003212-A1 | 3,5-DIHYDROXY-6,8-NONADIENOIC ACIDS AND DERIVATIVES AS HYPOCHOLESTEROLEMIC AGENTS | PFIZER INC. (US) | 1989-04-20 | — | — | WO | disclosed |
| EP-0312269-A2 | 3,5-Dihydroxy-6,8-nonadienoic acids and derivatives as hypocholesterolemic agents | PFIZER INC. (US) | 1989-04-19 | — | — | EP | disclosed |
| EP-0160252-A2 | Antibacterial compounds | Takeda Chemical Industries, Ltd. (JP) | 1985-11-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120018711-A1 | PLATINUM (II) TETRADENTATE ONCN COMPLEXES FOR ORGANIC LIGHT-EMITTING DIODE APPLICATIONS | PPOX, OCIAD2, PTN | ALDH1A1 1507/4885TRPA1 1074/4885LMNA 3508/4885 |
| US-20150344407-A1 | FENDILINE DERIVATIVES AND METHODS OF USE THEREOF | KRAS, RASSF5, RASSF2 | ALDH1A1 577/4885TRPA1 4135/4885LMNA 2538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.