SCHEMBL4087259

SCHEMBL4087259

C=C(C)C(=O)OCCOC(=O)c1cc(C(=O)O)c(C(=O)OCCOC(=O)C(=C)C)cc1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.47
TDP1 Q9NUW8 3/20 0.46
POLB P06746 1/20 0.46
APEX1 P27695 1/20 0.46
HTT P42858 1/20 0.46
TSHR P16473 7/20 0.42
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
SERPINE1 P05121 2/20 0.38
ALDH1A1 P00352 4/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.34
TP53 P04637 2/20 0.33
CYP3A4 P08684 2/20 0.33
MAPK1 P28482 2/20 0.33
NPC1 O15118 1/20 0.33
GLA P06280 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7080186 1.00 THRB (0.47) THRBTDP1POLBAPEX1HTT
SCHEMBL931727 1.00 THRB (0.47) THRBTDP1POLBAPEX1HTT
SCHEMBL1556947 1.00 THRB (0.47) THRBTDP1POLBAPEX1HTT
SCHEMBL19320457 0.95 THRB (0.44) THRBTDP1POLBAPEX1HTT
SCHEMBL10040690 0.93 THRB (0.53) THRBTDP1POLBAPEX1HTT
SCHEMBL13609931 0.93 SERPINE1 (0.43) THRBTDP1POLBAPEX1HTT
SCHEMBL29852036 0.91 THRB (0.41) THRBTDP1POLBAPEX1HTT
SCHEMBL16243539 0.88 TDP1 (0.46) THRBTDP1POLBAPEX1HTT
SCHEMBL19320455 0.88 THRB (0.49) THRBTDP1POLBAPEX1HTT
SCHEMBL13488730 0.88 POLB (0.43) THRBTDP1POLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4356169-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-04-24 EP claimed
CN-117280252-A Multifocal diffractive silicone hydrogel contact lenses 爱尔康公司 2023-12-22 CN claimed
WO-2022263994-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2022-12-22 WO claimed
CN-119410304-A Adhesive and application thereof in lithium battery 深圳好电科技有限公司 2025-02-11 CN disclosed
EP-4356169-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2024-04-24 EP disclosed
CN-117280252-A Multifocal diffractive silicone hydrogel contact lenses 爱尔康公司 2023-12-22 CN disclosed
WO-2022263994-A1 MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2022-12-22 WO disclosed
US-20160303015-A1 PHOTO-CROSSLINKABLE VARNISH COMPOSITIONS AS BASE COATING AND APPLICATION METHODS L'OREAL (FR) 2016-10-20 US disclosed
US-20160303015-A1 PHOTO-CROSSLINKABLE VARNISH COMPOSITIONS AS BASE COATING AND APPLICATION METHODS L'OREAL (FR) 2016-10-20 US disclosed
WO-2015082335-A1 PHOTO-CROSSLINKABLE VARNISH COMPOSITIONS AS BASE COATING AND APPLICATION METHODS L'OREAL (FR) 2015-06-11 WO disclosed
US-20120115108-A1 POLYMERIZABLE PHOSPHORIC ACID DERIVATIVES COMPRISING A POLYALICYLIC STRUCTURE ELEMENT VOCO GMBH (DE) 2012-05-10 US disclosed
US-20120115108-A1 POLYMERIZABLE PHOSPHORIC ACID DERIVATIVES COMPRISING A POLYALICYLIC STRUCTURE ELEMENT VOCO GMBH (DE) 2012-05-10 US disclosed
EP-2450025-A1 Polymerisable phosphoric acid derivatives comprising a polyalicyclic structure element VOCO GmbH (DE) 2012-05-09 EP disclosed
US-7777080-B2 Carboxylic acid derivatives containing phosphorous groups and organically polymerizable groups FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2010-08-17 US disclosed
US-7777080-B2 Carboxylic acid derivatives containing phosphorous groups and organically polymerizable groups FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2010-08-17 US disclosed
US-20100041790-A1 SELF-ETCHING DENTAL MATERIALS BASED ON (METH)ACRYLAMIDE PHOSPHATES IVOCLAR VIVADENT AG (LI) 2010-02-18 US disclosed
US-7622538-B2 Polymerizable dental material, characterized in that it contains at least one (meth)acrylamide phosphate; adhesives, coating materials and composites for dental purposes; hydrolysis-stable IVOCLAR VIVADENT AG (LI) 2009-11-24 US disclosed
EP-1674066-B1 Self-etching dental materials based on (meth)acrylamidophosphates IVOCLAR VIVADENT AG (LI) 2008-08-13 EP disclosed
US-20080057096-A1 Comprising stent body, first layer applied over stent body comprising a therapeutic substance and second layer applied over first layer comprising a fluoride-containing hydrophilic water insoluble crosslinked resin; biocompatible layer leaches fluoride to provide further therapy to patient DEN-MAT CORPORATION 2008-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041790-A1 SELF-ETCHING DENTAL MATERIALS BASED ON (METH)ACRYLAMIDE PHOSPHATES MSR1, C1R, HRH3 THRB 1471/4885TDP1 3866/4885POLB 938/4885
US-20080057096-A1 Comprising stent body, first layer applied over stent body comprising a therapeutic substance and second layer applied over first layer comprising a fluoride-containing hydrophilic water insoluble crosslinked resin; biocompatible layer leaches fluoride to provide further therapy to patient FGB, CSTB, FGFR2 THRB 922/4885TDP1 1517/4885POLB 3777/4885
US-20160303015-A1 PHOTO-CROSSLINKABLE VARNISH COMPOSITIONS AS BASE COATING AND APPLICATION METHODS POLR1C, ALK, TYR THRB 538/4885TDP1 330/4885POLB 84/4885
US-20120115108-A1 POLYMERIZABLE PHOSPHORIC ACID DERIVATIVES COMPRISING A POLYALICYLIC STRUCTURE ELEMENT CAD, PCBP1, PPIP5K2 THRB 3418/4885TDP1 1760/4885POLB 591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.