Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 7/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7080186 | 1.00 | THRB (0.47) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL931727 | 1.00 | THRB (0.47) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL4087259 | 1.00 | THRB (0.47) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL19320457 | 0.95 | THRB (0.44) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL10040690 | 0.93 | THRB (0.53) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL13609931 | 0.93 | SERPINE1 (0.43) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL29852036 | 0.91 | THRB (0.41) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL16243539 | 0.88 | TDP1 (0.46) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL19320455 | 0.88 | THRB (0.49) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL13488730 | 0.88 | POLB (0.43) | THRBTDP1POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12337043-B2 | Curable radiopaque substance | MERZ DENTAL GMBH (DE) | 2025-06-24 | — | — | US | claimed |
| US-20240225962-A9 | CURABLE RADIOPAQUE SUBSTANCE | MERZ DENTAL GMBH (DE) | 2024-07-11 | — | — | US | claimed |
| US-20240130933-A1 | CURABLE RADIOPAQUE SUBSTANCE | MERZ DENTAL GMBH (DE) | 2024-04-25 | — | — | US | claimed |
| US-11857649-B2 | Curable radiopaque substance | MERZ DENTAL GMBH (DE) | 2024-01-02 | — | — | US | claimed |
| US-20210228453-A1 | CURABLE RADIOPAQUE SUBSTANCE | MERZ DENTAL GMBH (DE) | 2021-07-29 | — | — | US | claimed |
| EP-3787701-A1 | CURABLE RADIOPAQUE SUBSTANCE | Merz Dental GmbH (DE) | 2021-03-10 | — | — | EP | claimed |
| US-12337043-B2 | Curable radiopaque substance | MERZ DENTAL GMBH (DE) | 2025-06-24 | — | — | US | disclosed |
| US-20240225962-A9 | CURABLE RADIOPAQUE SUBSTANCE | MERZ DENTAL GMBH (DE) | 2024-07-11 | — | — | US | disclosed |
| US-20240130933-A1 | CURABLE RADIOPAQUE SUBSTANCE | MERZ DENTAL GMBH (DE) | 2024-04-25 | — | — | US | disclosed |
| US-11857649-B2 | Curable radiopaque substance | MERZ DENTAL GMBH (DE) | 2024-01-02 | — | — | US | disclosed |
| US-20210228453-A1 | CURABLE RADIOPAQUE SUBSTANCE | MERZ DENTAL GMBH (DE) | 2021-07-29 | — | — | US | disclosed |
| EP-2123246-B1 | ADHESIVE COMPOSITION FOR DENTAL USE | TOKUYAMA DENTAL CORP (JP) | 2021-06-23 | — | — | EP | disclosed |
| EP-3787701-A1 | CURABLE RADIOPAQUE SUBSTANCE | Merz Dental GmbH (DE) | 2021-03-10 | — | — | EP | disclosed |
| US-20110278049-A1 | PHOTOSENSITIVE RESIN COMPOSITION AND DRY FILM COMPRISING THE SAME | LG CHEM, LTD. (KR) | 2011-11-17 | — | — | US | disclosed |
| US-20110278049-A1 | PHOTOSENSITIVE RESIN COMPOSITION AND DRY FILM COMPRISING THE SAME | LG CHEM, LTD. (KR) | 2011-11-17 | — | — | US | disclosed |
| US-20110098375-A1 | DENTAL ADHESIVE COMPOSITION | TOKUYAMA DENTAL CORPORATION (JP) | 2011-04-28 | — | — | US | disclosed |
| EP-2305205-A1 | DENTAL ADHESIVE COMPOSITION | Tokuyama Dental Corporation (JP) | 2011-04-06 | — | — | EP | disclosed |
| US-20100317762-A1 | ADHESIVE COMPOSITION FOR DENTAL USE | TOKUYAMA DENTAL CORPORATION | 2010-12-16 | — | — | US | disclosed |
| EP-2123246-A1 | ADHESIVE COMPOSITION FOR DENTAL USE | Tokuyama Dental Corporation (JP) | 2009-11-25 | — | — | EP | disclosed |
| US-20080057096-A1 | Comprising stent body, first layer applied over stent body comprising a therapeutic substance and second layer applied over first layer comprising a fluoride-containing hydrophilic water insoluble crosslinked resin; biocompatible layer leaches fluoride to provide further therapy to patient | DEN-MAT CORPORATION | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080057096-A1 | Comprising stent body, first layer applied over stent body comprising a therapeutic substance and second layer applied over first layer comprising a fluoride-containing hydrophilic water insoluble crosslinked resin; biocompatible layer leaches fluoride to provide further therapy to patient | FGB, CSTB, FGFR2 | THRB 922/4885TDP1 1517/4885POLB 3777/4885 |
| US-20100317762-A1 | ADHESIVE COMPOSITION FOR DENTAL USE | ITGA1, VMA21, ITGA6 | THRB 259/4885TDP1 937/4885POLB 2366/4885 |
| US-20110098375-A1 | DENTAL ADHESIVE COMPOSITION | CAD, CDH1, ITGA4 | THRB 628/4885TDP1 2634/4885POLB 1223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.