SCHEMBL409063

SCHEMBL409063

CC1CNCC[N+]1(C)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 3/20 0.35
HTR2A P28223 1/20 0.35
HTR2B P41595 1/20 0.35
SLC6A2 P23975 2/20 0.31
SLC6A4 P31645 2/20 0.31
SLC6A3 Q01959 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL11457679 0.98 HTR2C (0.34) HTR2CHTR2AHTR2BSLC6A2SLC6A4
Hydrochloric Acid SCHEMBL118973 0.98 HTR2C (0.34) HTR2CHTR2AHTR2BSLC6A2SLC6A4
Hydrochloric Acid SCHEMBL27986246 0.98 HTR2C (0.34) HTR2CHTR2AHTR2BSLC6A2SLC6A4
Iodide SCHEMBL11457678 0.64 SLC18A3 (0.37)
Hydrochloric Acid SCHEMBL6830548 0.64 SLC18A3 (0.37)
Hydrochloric Acid SCHEMBL22031619 0.63
Iodide SCHEMBL22031617 0.63
SCHEMBL4907271 0.63 ORAI1 (0.40) HTR2CHTR2ASLC6A2SLC6A4
SCHEMBL8331771 0.62
SCHEMBL5281905 0.61 APOBEC3A (0.37) HTR2AHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250026696-A1 Novel Humic Material and Method to Formulate the Same MEYER MICHAEL J (US) 2025-01-23 US claimed
US-20230078902-A1 Novel Method to Formulate Humic Substances MEYER MICHAEL J (US) 2023-03-16 US claimed
WO-2023279162-A1 METHODS OF TREATMENT AND INHIBITION UNIVERSITY OF CANBERRA (AU) 2023-01-12 WO claimed
US-11548833-B2 Method to formulate humic substances MEYER MICHAEL J (US) 2023-01-10 US claimed
US-20200385320-A1 Method to Formulate Humic Substances MEYER MICHAEL J (US) 2020-12-10 US claimed
US-10568852-B2 Combination compositions and their use in methods for treating obesity and obesity-related disorders HELMHOLTZ ZENTRUM MUNCHEN - DEUTSCHES FORSCHUNGSZENTRUM FUR GESUNDHEIT UND UMWELT (GMBH) (DE) 2020-02-25 US claimed
US-20180147163-A1 COMBINATION COMPOSITIONS AND THEIR USE IN METHODS FOR TREATING OBESITY AND OBESITY-RELATED DISORDERS HELMHOLTZ ZENTRUM MUNCHEN - DEUTSCHES FORSCHUNGSZENTRUM FUR GESUNDHEIT UND UMWELT (GMBH) (DE) 2018-05-31 US claimed
EP-3297676-A2 COMBINATION OF TRPM8-AGONIST AND NACHR-AGONIST FOR TREATMENT OF OBESITY AND RELATED DISORDERS AND FOR WEIGHT REDUCTION Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) 2018-03-28 EP claimed
US-20170348430-A1 MICELAR DELIVERY SYSTEM BASED ON ENZYME-RESPONSIVE AMPHIPHILIC PEG-DENDRON HYBRID RAMOT AT TEL AVIV UNlVERSITY LTD. (IL) 2017-12-07 US claimed
EP-3191137-A1 MICELAR DELIVERY SYSTEM BASED ON ENZYME-RESPONSIVE AMPHIPHILIC PEG-DENDRON HYBRID Ramot at Tel-Aviv University Ltd. (IL) 2017-07-19 EP claimed
EP-1773779-A1 NICOTINIC RECEPTOR AGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES UNIVERSITE LAVAL (CA) 2007-04-18 EP claimed
WO-2006005195-A1 NICOTINIC RECEPTOR AGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES UNIVERSITé LAVAL (CA) 2006-01-19 WO claimed
WO-2005117860-A1 METHOD OF TREATING AND PREVENTING ARTHRITIS, CUTANEOUS AND CARDIOVASCULAR INFLAMMATORY-RELATED DISEASES USING NICOTINIC RECEPTOR AGONISTS ASMACURE LTÉE (CA) 2005-12-15 WO claimed
US-20050130990-A1 Nicotinic receptor agonists for the treatment of inflammatory diseases UNIVERSITE LAVAL (CA) 2005-06-16 US claimed
CN-1610714-A Polycarbonate-siloxane copolymers GEN ELECTRIC (US) 2005-04-27 CN claimed
JP-2004523588-A 2004-08-05 JP claimed
US-20040132737-A1 Nicotinic receptor agonists for the treatment of inflammatory diseases UNIVERSITE LAVAL (CA) 2004-07-08 US claimed
CN-1498108-A Nicotinic receptor agonists for treatment of inflammatory diseases �Ϻ���ͨ��ѧ 2004-05-19 CN claimed
EP-1370264-A2 NICOTINIC RECEPTOR AGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES Université Laval (CA) 2003-12-17 EP claimed
WO-2002076434-A2 NICOTINIC RECEPTOR AGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES UNIVERSITE LAVAL (CA) 2002-10-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10568852-B2 Combination compositions and their use in methods for treating obesity and obesity-related disorders FABP4, LIPC, GPR119 HTR2C 1078/4885HTR2A 1019/4885HTR2B 1733/4885
US-20180147163-A1 COMBINATION COMPOSITIONS AND THEIR USE IN METHODS FOR TREATING OBESITY AND OBESITY-RELATED DISORDERS FABP4, LIPC, GPR119 HTR2C 1078/4885HTR2A 1019/4885HTR2B 1733/4885
US-20170348430-A1 MICELAR DELIVERY SYSTEM BASED ON ENZYME-RESPONSIVE AMPHIPHILIC PEG-DENDRON HYBRID KIT, JMJD7, LIPA HTR2C 4393/4885HTR2A 4225/4885HTR2B 3793/4885
US-20050130990-A1 Nicotinic receptor agonists for the treatment of inflammatory diseases CHRNA1, NR3C1, CHRNG HTR2C 640/4885HTR2A 478/4885HTR2B 466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.