Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4090888 | 0.83 | MEN1 (0.37) | MEN1KMT2AAOC3 | |
| SCHEMBL153435 | 0.75 | GABRA1 (0.37) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL215519 | 0.75 | TSHR (0.45) | MEN1KMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL23121590 | 0.70 | PNMT (0.43) | NOS3NOS1NOS2KCNH2 | |
| SCHEMBL635206 | 0.70 | PNMT (0.43) | NOS3NOS1NOS2KCNH2 | |
| SCHEMBL14131092 | 0.70 | POLB (0.56) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL10654891 | 0.70 | AOC3 (0.55) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL15592332 | 0.69 | KMT2A (0.46) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8809480 | 0.69 | MAPT (0.51) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL14052664 | 0.68 | PDK1 (0.58) | MEN1KMT2AMAPTHPSERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146723-A | CHEMICAL AND TEMPERATURE RESISTANT | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-27 | — | — | US | disclosed |