SCHEMBL905272

SCHEMBL905272

CC[CH][SiH2]C(OCCCC)OCCCC

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.32
ADRB2 P07550 1/20 0.32
ADRB1 P08588 1/20 0.32
ADRB3 P13945 1/20 0.32
ATM Q13315 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4079093 0.86
SCHEMBL4090915 0.80 DNM1 (0.33) DNM1ADRB2ADRB1ADRB3ATM
SCHEMBL557068 0.78 TSHR (0.36) DNM1ADRB2ADRB1ADRB3ATM
SCHEMBL7935124 0.72 DNM1 (0.39) DNM1ALDH1A1CNR1CNR2
SCHEMBL4092993 0.72 ADRB2 (0.38) DNM1ADRB2ADRB1ADRB3ATM
SCHEMBL7937310 0.71 DNM1 (0.42) DNM1ALDH1A1CNR1CNR2
SCHEMBL703587 0.70 ADRB2 (0.36) DNM1ADRB2ADRB1ADRB3ALDH1A1
SCHEMBL703595 0.70 ADRB2 (0.36) DNM1ADRB2ADRB1ADRB3ALDH1A1
SCHEMBL4092985 0.70 ADRB2 (0.36) DNM1ADRB2ADRB1ADRB3ALDH1A1
SCHEMBL705365 0.68 ADRB2 (0.35) DNM1ADRB2ADRB1ADRB3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1915399-B1 RECOVERABLE POLYMER-BOUND HOMOGENEOUS CATALYSTS FOR CATALYTIC CHAIN TRANSFER PROCESSES COATINGS FOREIGN IP CO LLC (US) 2013-11-20 EP claimed
US-8030422-B2 Recoverable polymer-bound homogeneous catalysts for catalytic chain transfer process E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-10-04 US claimed
EP-2272885-A2 Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom Lubrizol Advanced Materials, Inc. (US) 2011-01-12 EP claimed
EP-1915399-A1 RECOVERABLE POLYMER-BOUND HOMOGENEOUS CATALYSTS FOR CATALYTIC CHAIN TRANSFER PROCESSES E.I.Du pont de nemours and company (US) 2008-04-30 EP claimed
WO-2007024634-A1 RECOVERABLE POLYMER-BOUND HOMOGENEOUS CATALYSTS FOR CATALYTIC CHAIN TRANSFER PROCESSES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-03-01 WO claimed
EP-0791016-A1 POLYMER SYNTHESIS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-08-27 EP claimed
WO-1996015157-A1 POLYMER SYNTHESIS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-05-23 WO claimed
EP-2970538-B1 POLYMERIZATION PROCESS PROTECTION MEANS DUPONT ELECTRONICS INC (US) 2021-10-20 EP disclosed
CN-107428955-B Proton binding polymers for oral administration 特里赛达公司 2021-09-21 CN disclosed
US-9925214-B2 Proton-binding polymers for oral administration TRICIDA, INC. (US) 2018-03-27 US disclosed
WO-2016123675-A1 TARGETING CONSTRUCTS FOR DELIVERY OF PAYLOADS THE UNIVERSITY OF QUEENSLAND (AU) 2016-08-11 WO disclosed
US-20160074430-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION RENIBUS THERAPEUTICS, INC. 2016-03-17 US disclosed
EP-2970538-A1 POLYMERIZATION PROCESS PROTECTION MEANS E. I. du Pont de Nemours and Company (US) 2016-01-20 EP disclosed
WO-2007094858-A2 PROCESS FOR AMINATION OF ACRYLIC MACROMONOMERS AND PRODUCTS THEREFROM E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-08-23 WO disclosed
US-20070161675-A1 PROCESSES FOR HYDRAZINE ADDITION TO ACRYLIC MACROMONOMERS AND PRODUCTS THEREFROM E. I. DUPONT DE NEMOURS AND COMPANY (US) 2007-07-12 US disclosed
WO-2007070724-A2 PIGMENT DISPERSIONS CONTAINING AMINATED ACRYLIC MACROMONOMER DISPERSANT E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-06-21 WO disclosed
US-20070142546-A1 Pigment dispersions containing aminated acrylic macromonomer dispersant AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2007-06-21 US disclosed
WO-2007024634-A1 RECOVERABLE POLYMER-BOUND HOMOGENEOUS CATALYSTS FOR CATALYTIC CHAIN TRANSFER PROCESSES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-03-01 WO disclosed
EP-1639019-A1 PRESSURIZED HIGH TEMPERATURE POLYMERIZATION PROCESS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-03-29 EP disclosed
WO-2005003185-A1 PRESSURIZED HIGH TEMPERATURE POLYMERIZATION PROCESS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160074430-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION SLC9A1, HRH2, SLC9A2 DNM1 650/4885ADRB2 4338/4885ADRB1 4371/4885
US-20070161675-A1 PROCESSES FOR HYDRAZINE ADDITION TO ACRYLIC MACROMONOMERS AND PRODUCTS THEREFROM HNMT, BHMT2, BHMT DNM1 1248/4885ADRB2 3940/4885ADRB1 3802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.