Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4091076 | 1.00 | SIRT6 (0.41) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL19475625 | 0.87 | PDGFRB (0.41) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL15687421 | 0.87 | PDGFRB (0.41) | SIRT6PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL30083324 | 0.86 | ALDH1A1 (0.46) | TDP1MAPTALDH1A1STAT3LMNA | |
| SCHEMBL396046 | 0.86 | ALDH1A1 (0.46) | TDP1MAPTALDH1A1STAT3LMNA | |
| SCHEMBL21681922 | 0.86 | MAPT (0.46) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL396045 | 0.86 | ALDH1A1 (0.46) | TDP1MAPTALDH1A1STAT3LMNA | |
| SCHEMBL12869675 | 0.86 | MAPT (0.46) | PDGFRBFGFR1PDGFRAFLT1FGFR3 | |
| SCHEMBL16840175 | 0.85 | STAT3 (0.40) | PTGS2TDP1MAPTALDH1A1STAT3 | |
| SCHEMBL1465976 | 0.85 | PTGS2 (0.42) | PTGS2MAPTALDH1A1STAT3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090214529-A9 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2009-08-27 | — | — | US | disclosed |
| WO-2008147852-A1 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2008-12-04 | — | — | WO | disclosed |
| US-20080292626-A1 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090214529-A9 | KINESIN INHIBITORS | KIF5B, KIF5A, KIF5C | SIRT6 2197/4885PDGFRB 4019/4885FGFR1 1920/4885 |
| US-20080292626-A1 | KINESIN INHIBITORS | KIF5B, KIF5A, KIF5C | SIRT6 2197/4885PDGFRB 4019/4885FGFR1 1920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.