SCHEMBL4091105

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5647619	0.85	TDP1 (0.55)	PDE4APDE4BPDE4CPDE4DLMNA
	SCHEMBL5106062	0.82	PDE4A (0.51)	PDE4APDE4BPDE4CPDE4DLMNA
	SCHEMBL14078125	0.82	PDE4A (0.49)	PDE4APDE4BPDE4CPDE4DLMNA
	SCHEMBL14078123	0.82	PDE4A (0.48)	PDE4APDE4BPDE4CPDE4DLMNA
	SCHEMBL5111971	0.81	PDE4A (0.50)	PDE4APDE4BPDE4CPDE4DLMNA
	SCHEMBL4314434	0.81	PDE4A (0.52)	PDE4APDE4BPDE4CPDE4DLMNA
	SCHEMBL4263303	0.78	ALDH1A1 (0.42)	PDE4APDE4BPDE4CPDE4DLMNA
	SCHEMBL14367275	0.78	PDE4A (0.69)	PDE4APDE4BPDE4CPDE4DLMNA
	SCHEMBL4098315	0.78	LMNA (0.48)	PDE4APDE4BPDE4CPDE4DLMNA
	SCHEMBL5062320	0.77	PDE4A (0.47)	PDE4APDE4BPDE4CPDE4DLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.