SCHEMBL4098315

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4752671	0.88	PDE4A (0.42)	LMNAMEN1KMT2ATLR7ALOX5AP
	SCHEMBL5118726	0.82	PDE4A (0.50)	LMNAMEN1KMT2ATLR7PDE4A
	SCHEMBL5106687	0.81	LMNA (0.50)	LMNAMEN1KMT2ATLR7ALOX5AP
	SCHEMBL5108726	0.78	MEN1 (0.46)	LMNAMEN1KMT2ATLR7ALOX5AP
	SCHEMBL13981796	0.78	CACNA2D1 (0.40)	LMNAMEN1KMT2AALOX5APPDE4A
	SCHEMBL4109641	0.78	ALDH1A1 (0.41)	LMNAMEN1KMT2AALOX5APPDE4A
	SCHEMBL14367275	0.78	PDE4A (0.69)	LMNAMEN1KMT2ATLR7PDE4A
	SCHEMBL4091105	0.78	PDE4A (0.51)	LMNAMEN1KMT2ATLR7PDE4A
	SCHEMBL5120052	0.77	CYP1A2 (0.53)	LMNAMEN1KMT2ATLR7PDE4A
	SCHEMBL5119264	0.76	PDE4A (0.51)	LMNAMEN1KMT2ATLR7PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.