Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4094548 | 0.71 | KDM4E (0.42) | SMN1; SMN2LMNANPY2RMEN1KMT2A | |
| SCHEMBL8283520 | 0.71 | MAPT (0.52) | SMN1; SMN2LMNAL3MBTL1KMT2ABLM | |
| SCHEMBL12928720 | 0.69 | L3MBTL1 (0.52) | SMN1; SMN2LMNAL3MBTL1BLMCYP2D6 | |
| SCHEMBL505194 | 0.69 | L3MBTL1 (0.52) | SMN1; SMN2LMNAL3MBTL1POLBKMT2A | |
| SCHEMBL4097648 | 0.68 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAL3MBTL1POLBNPY2R | |
| SCHEMBL10697753 | 0.68 | L3MBTL1 (0.43) | SMN1; SMN2LMNACYP19A1L3MBTL1BLM | |
| SCHEMBL25511737 | 0.68 | L3MBTL1 (0.50) | SMN1; SMN2LMNAL3MBTL1POLBBLM | |
| SCHEMBL25464082 | 0.67 | GRM5 (0.49) | SMN1; SMN2NPY2RKMT2ATSHRRAB9A | |
| SCHEMBL10696448 | 0.66 | KEAP1 (0.44) | SMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL504847 | 0.65 | PLCG1 (0.51) | SMN1; SMN2CYP19A1L3MBTL1BLMCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082367-A1 | TRIAZOLE DERIVATIVE OR A SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2009-03-26 | — | — | US | disclosed |
| EP-1995243-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2008-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082367-A1 | TRIAZOLE DERIVATIVE OR A SALT THEREOF | HSD11B1, HSD11B2, HSD17B1 | SMN1; SMN2 3838/4885LMNA 4107/4885CYP19A1 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.