Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.30 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31357864 | 0.79 | CYP1A2 (0.35) | PDE4BALDH1A1CYP1A2CYP2A6 | |
| SCHEMBL4084945 | 0.76 | DYRK1A (0.41) | ALDH1A1 | |
| SCHEMBL4095742 | 0.74 | BRD4 (0.40) | ALDH1A1 | |
| SCHEMBL14689705 | 0.70 | ALDH1A1 (0.40) | ALDH1A1CYP1A2CYP2A6 | |
| SCHEMBL22938909 | 0.69 | TTR (0.39) | ALDH1A1 | |
| SCHEMBL4095238 | 0.68 | KCNH2 (0.35) | ALDH1A1CYP1A2 | |
| SCHEMBL4089998 | 0.67 | MEN1 (0.40) | PDE4BALDH1A1GRM2 | |
| SCHEMBL4082423 | 0.66 | SLC6A2 (0.44) | GRM2 | |
| SCHEMBL23491105 | 0.62 | ALKBH5 (0.42) | ALDH1A1CYP1A2CYP2A6GRM2 | |
| SCHEMBL31582707 | 0.62 | KDM4E (0.39) | ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009055674-A1 | PYRROLOPYRIMIDINE ALKYNYL COMPOUNDS AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-04-30 | — | — | WO | disclosed |
| WO-2009055674-A1 | PYRROLOPYRIMIDINE ALKYNYL COMPOUNDS AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-04-30 | — | — | WO | disclosed |