Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 2/20 | 0.41 |
| ▸ | ADH1A | P07327 | 2/20 | 0.41 |
| ▸ | ADH7 | P40394 | 2/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4086191 | 0.76 | FFAR1 (0.42) | ADH1BADH1AADH7ADH1CHPGD | |
| SCHEMBL45854 | 0.75 | — | — | |
| SCHEMBL4090622 | 0.74 | LOX (0.50) | ADH1BADH1AADH7ADH1CL3MBTL1 | |
| SCHEMBL4096480 | 0.74 | PRMT6 (0.61) | HPGDALDH1A1RAB9ASMN1; SMN2PRMT6 | |
| SCHEMBL15330274 | 0.73 | ALDH1A1 (0.36) | HPGDALDH1A1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL4091445 | 0.73 | ADH1B (0.35) | ADH1BADH1AADH7ADH1CPRMT6 | |
| SCHEMBL22953834 | 0.72 | PRMT6 (0.39) | HPGDALDH1A1RAB9ASMN1; SMN2PRMT6 | |
| SCHEMBL18725105 | 0.72 | ALDH1A1 (0.41) | HPGDALDH1A1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL13185590 | 0.71 | CD274 (0.42) | HPGDALDH1A1RAB9ASMN1; SMN2PRMT6 | |
| SCHEMBL13024414 | 0.69 | RAB9A (0.48) | HPGDALDH1A1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | STERIX LIMITED (GB) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042929-A1 | 11-Beta-Hydroxysteroid Dehydrogenase Inhibitors | HSD3B1, HSD3B2, HSD11B1 | ADH1B 127/4885ADH1A 227/4885ADH7 88/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.