Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4097426 | 0.86 | RAB9A (0.53) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL4471234 | 0.85 | RAB9A (0.49) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL11834939 | 0.85 | RAB9A (0.39) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL4103672 | 0.85 | KMT2A (0.56) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL11835118 | 0.85 | NPC1 (0.47) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL16701793 | 0.83 | KMT2A (0.54) | RAB9ANPC1KMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL21645501 | 0.83 | F2 (0.39) | RAB9ANPC1 | |
| SCHEMBL3068902 | 0.80 | F2 (0.43) | RAB9ANPC1ALDH1A1HPGDTSHR | |
| Hydrochloric Acid SCHEMBL21645351 | 0.80 | EGFR (0.34) | — | |
| SCHEMBL3674744 | 0.79 | ALDH1A1 (0.53) | RAB9ANPC1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110357795-A | A kind of Biguanide derivative, pharmaceutical composition, preparation method and its application in preparation of anti-tumor drugs | 湖南师范大学 | 2019-10-22 | — | — | CN | claimed |
| US-20170114008-A1 | NOVEL COMPOUND HAVING IMMUNE DISEASE TREATMENT EFFECT AND USE THEREOF | THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2017-04-27 | — | — | US | claimed |
| CN-110357795-A | A kind of Biguanide derivative, pharmaceutical composition, preparation method and its application in preparation of anti-tumor drugs | 湖南师范大学 | 2019-10-22 | — | — | CN | disclosed |
| US-10100006-B2 | Compound having immune disease treatment effect and use thereof | THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2018-10-16 | — | — | US | disclosed |
| US-20180118668-A1 | NOVEL COMPOUND HAVING IMMUNE DISEASE TREATMENT EFFECT AND USE THEREOF | THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2018-05-03 | — | — | US | disclosed |
| US-20180118668-A1 | NOVEL COMPOUND HAVING IMMUNE DISEASE TREATMENT EFFECT AND USE THEREOF | THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2018-05-03 | — | — | US | disclosed |
| US-20180118668-A1 | NOVEL COMPOUND HAVING IMMUNE DISEASE TREATMENT EFFECT AND USE THEREOF | THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2018-05-03 | — | — | US | disclosed |
| US-20170114008-A1 | NOVEL COMPOUND HAVING IMMUNE DISEASE TREATMENT EFFECT AND USE THEREOF | THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2017-04-27 | — | — | US | disclosed |
| US-20170114008-A1 | NOVEL COMPOUND HAVING IMMUNE DISEASE TREATMENT EFFECT AND USE THEREOF | THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2017-04-27 | — | — | US | disclosed |
| US-20170114008-A1 | NOVEL COMPOUND HAVING IMMUNE DISEASE TREATMENT EFFECT AND USE THEREOF | THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2017-04-27 | — | — | US | disclosed |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | MALLE GERARD | 2009-08-06 | — | — | US | disclosed |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | L'OREAL S.A. | 2009-06-04 | — | — | US | disclosed |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | disclosed |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | L'OREAL | 2005-06-16 | — | — | US | disclosed |
| EP-1532963-A1 | Composition for straightening the hair comprising at least one imine not being an hydroxide | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| EP-1532960-A1 | Hair styling composition containing a non-hydroxide imine | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | KRT18, INMT, INHA | RAB9A 2870/4885NPC1 4841/4885KMT2A 322/4885 |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | KRT18, KIT, PRDM7 | RAB9A 1539/4885NPC1 4782/4885KMT2A 555/4885 |
| US-20170114008-A1 | NOVEL COMPOUND HAVING IMMUNE DISEASE TREATMENT EFFECT AND USE THEREOF | NFATC1, CD14, CD209 | RAB9A 358/4885NPC1 1585/4885KMT2A 2342/4885 |
| US-20180118668-A1 | NOVEL COMPOUND HAVING IMMUNE DISEASE TREATMENT EFFECT AND USE THEREOF | NFATC1, CD14, CD209 | RAB9A 358/4885NPC1 1585/4885KMT2A 2342/4885 |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | KRT18, INHA, H1-5 | RAB9A 2224/4885NPC1 4747/4885KMT2A 949/4885 |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | BHMT, KRT18, INMT | RAB9A 1450/4885NPC1 4179/4885KMT2A 665/4885 |
| US-10100006-B2 | Compound having immune disease treatment effect and use thereof | NFATC1, CD14, CD209 | RAB9A 464/4885NPC1 1584/4885KMT2A 2372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.