Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4097428 | 0.86 | RAB9A (0.44) | RAB9ANPC1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL11256285 | 0.86 | PLAU (0.43) | RAB9ANPC1ALDH1A1TSHRMEN1 | |
| SCHEMBL6699635 | 0.86 | MAOB (0.47) | RAB9ANPC1ALDH1A1MAPTMAOB | |
| SCHEMBL4103669 | 0.86 | SLC2A1 (0.56) | RAB9ANPC1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL6698612 | 0.86 | IDO1 (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11255183 | 0.86 | KIF11 (0.49) | RAB9ANPC1ALDH1A1LMNAMAPT | |
| SCHEMBL11253879 | 0.86 | PLAU (0.46) | RAB9ANPC1ALDH1A1TP53MEN1 | |
| SCHEMBL11259118 | 0.84 | KCNQ3 (0.45) | ALDH1A1SMN1; SMN2TSHRLMNAMAPK1 | |
| SCHEMBL4795850 | 0.82 | ALDH1A1 (0.61) | RAB9ANPC1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL11258189 | 0.81 | LMNA (0.46) | RAB9ANPC1ALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | MALLE GERARD | 2009-08-06 | — | — | US | disclosed |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | L'OREAL S.A. | 2009-06-04 | — | — | US | disclosed |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | disclosed |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | L'OREAL | 2005-06-16 | — | — | US | disclosed |
| EP-1532963-A1 | Composition for straightening the hair comprising at least one imine not being an hydroxide | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| EP-1532960-A1 | Hair styling composition containing a non-hydroxide imine | L'OREAL (FR) | 2005-05-25 | — | — | EP | disclosed |
| US-4562209-A | Promotion of feed efficiency in animals | WILLIAM H. RORER, INC. (US) | 1985-12-31 | — | — | US | disclosed |
| EP-0086193-A1 | THE TREATMENT AND PREVENTION OF SCOURS IN ANIMALS | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1983-08-24 | — | — | EP | disclosed |
| EP-0073276-A1 | A method of increasing the feed efficiency of animals, and compositions for use in such a method | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1983-03-09 | — | — | EP | disclosed |
| WO-1983000626-A1 | THE TREATMENT AND PREVENTION OF SCOURS IN ANIMALS | RORER INT OVERSEAS (US) | 1983-03-03 | — | — | WO | disclosed |
| US-4340609-A | Amidinourea derivative veterinary compositions for suppression of parasitemia | WILLIAM H. RORER, INC. (US) | 1982-07-20 | — | — | US | disclosed |
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |
| US-4285972-A | Method of treating scours | WILLIAM H. RORER, INC. (US) | 1981-08-25 | — | — | US | disclosed |
| US-4115564-A | Treatment of diarrhea with amidinoureas | WILLIAM H. RORER, INC. (US) | 1978-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | KRT18, INMT, INHA | RAB9A 2870/4885NPC1 4841/4885ALDH1A1 1963/4885 |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | KRT18, KIT, PRDM7 | RAB9A 1539/4885NPC1 4782/4885ALDH1A1 1279/4885 |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | KRT18, INHA, H1-5 | RAB9A 2224/4885NPC1 4747/4885ALDH1A1 1073/4885 |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | BHMT, KRT18, INMT | RAB9A 1450/4885NPC1 4179/4885ALDH1A1 1610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.