Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2202005 | 0.73 | RAPGEF4 (0.55) | ALDH1A1RAPGEF4 | |
| SCHEMBL11662838 | 0.73 | TSHR (0.41) | L3MBTL1KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL25598687 | 0.69 | TSHR (0.38) | L3MBTL1KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL15478488 | 0.68 | RAPGEF4 (0.52) | L3MBTL1HSD17B2ALDH1A1RAPGEF4 | |
| SCHEMBL30908390 | 0.68 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1 | |
| SCHEMBL3796970 | 0.67 | KEAP1 (0.50) | L3MBTL1KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL29604136 | 0.67 | KEAP1 (0.50) | L3MBTL1KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL12307 | 0.66 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1RAPGEF4 | |
| SCHEMBL28278788 | 0.66 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1RAPGEF4 | |
| SCHEMBL12152328 | 0.65 | LMNA (0.40) | L3MBTL1ALDH1A1RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029706-A2 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | ExxonMobil Research and Engineering Company (US) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007133462-A2 | LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2007-11-22 | — | — | WO | disclosed |