Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18000197 | 0.76 | CMA1 (0.37) | ALDH1A1MDM2LMNAMAOAMAOB | |
| SCHEMBL1885008 | 0.73 | KMT2A (0.42) | ALDH1A1DHFRSLC2A1SMN1; SMN2LMNA | |
| SCHEMBL19643772 | 0.73 | DHFR (0.43) | ALDH1A1DHFRSLC2A1SMN1; SMN2LMNA | |
| SCHEMBL4081070 | 0.70 | CSNK1E (0.36) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4082423 | 0.67 | SLC6A2 (0.44) | — | |
| SCHEMBL1272210 | 0.65 | TYMS (0.45) | ALDH1A1SMN1; SMN2MDM2LMNA | |
| SCHEMBL4083412 | 0.64 | NOS1 (0.34) | SMN1; SMN2LMNA | |
| SCHEMBL19121794 | 0.64 | KDM4E (0.40) | ALDH1A1 | |
| SCHEMBL14627848 | 0.64 | LMNA (0.47) | ALDH1A1LMNAMCOLN3 | |
| SCHEMBL20356287 | 0.64 | HTR2A (0.41) | ALDH1A1DHFRSLC2A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009055674-A1 | PYRROLOPYRIMIDINE ALKYNYL COMPOUNDS AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-04-30 | — | — | WO | disclosed |
| WO-2009055674-A1 | PYRROLOPYRIMIDINE ALKYNYL COMPOUNDS AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-04-30 | — | — | WO | disclosed |