Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.55 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10767920 | 1.00 | CES2 (0.55) | CES2CES1MEN1FAAHMAPK1 | |
| SCHEMBL29222355 | 1.00 | CES2 (0.55) | CES2CES1MEN1FAAHMAPK1 | |
| Dimethylamine SCHEMBL28647653 | 0.94 | CES2 (0.50) | CES2CES1MEN1FAAHMAPK1 | |
| SCHEMBL3096915 | 0.83 | CES2 (0.59) | CES2CES1ALDH1A1TSHRSLC22A6 | |
| SCHEMBL3099780 | 0.83 | CES2 (0.59) | CES2CES1ALDH1A1TSHRSLC22A6 | |
| SCHEMBL3114101 | 0.83 | CES2 (0.59) | CES2CES1ALDH1A1TSHRSLC22A6 | |
| SCHEMBL3099789 | 0.83 | CES2 (0.59) | CES2CES1ALDH1A1TSHRSLC22A6 | |
| SCHEMBL515289 | 0.83 | CES2 (0.59) | CES2CES1ALDH1A1TSHRSLC22A6 | |
| SCHEMBL515288 | 0.83 | CES2 (0.59) | CES2CES1ALDH1A1TSHRSLC22A6 | |
| SCHEMBL3096900 | 0.83 | CES2 (0.59) | CES2CES1ALDH1A1TSHRSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817045-B1 | AN OIL-IN-WATER NANOEMULSION, A COSMETIC COMPOSITION AND A COSMETIC PRODUCT COMPRISING IT, A PROCESS FOR PREPARING SAID NANOEMULSION | NATURA COSMETICOS SA (BR) | 2017-12-27 | — | — | EP | disclosed |
| US-9198848-B2 | Process for obtaining extracts containing methylxanthine derivatives from cakes of plants of the genus Theobroma, as well as composition and use of said extract | NATURA COSMETICOS S.A. (BR) | 2015-12-01 | — | — | US | disclosed |
| EP-2373283-B1 | PROCESS FOR OBTAINING EXTRACTS CONTAINING METHYLXANTHINE DERIVATIVES FROM CAKES OF PLANTS OF THE GENUS THEOBROMA, AS WELL AS COMPOSITION AND USE OF SAID EXTRACT | NATURA COSMETICOS SA (BR) | 2015-02-18 | — | — | EP | disclosed |
| US-8956597-B2 | Oil-in-water nanoemulsion, a cosmetic composition and a cosmetic product comprising it, a process for preparing said nanoemulsion | NATURA COSMETICOS S.A. (BR) | 2015-02-17 | — | — | US | disclosed |
| US-20120172326-A1 | Moisturizing Mixture, Cosmetic And/Or Pharmaceutical Compositions Containing The Moisturizing Mixture, Use Of The Moisturizing Mixture, And Cosmetic Method | NATURA COSMETICOS S.A. (BR) | 2012-07-05 | — | — | US | disclosed |
| US-20120022085-A1 | PROCESS FOR OBTAINING EXTRACTS CONTAINING METHYLXANTHINE DERIVATIVES FROM CAKES OF PLANTS OF THE GENUS THEOBROMA, AS WELL AS COMPOSITION AND USE OF SAID EXTRACT | NATURA COSMETICOS S.A. (BR) | 2012-01-26 | — | — | US | disclosed |
| EP-2381917-A1 | MOISTURIZING MIXTURE, COSMETIC AND/OR PHARMACEUTICAL COMPOSITIONS CONTAINING THE MOISTURIZING MIXTURE, USE OF THE MOISTURIZING MIXTURE, AND COSMETIC METHOD | Natura Cosméticos S.A. (BR) | 2011-11-02 | — | — | EP | disclosed |
| EP-2373283-A2 | PROCESS FOR OBTAINING EXTRACTS CONTAINING METHYLXANTHINE DERIVATIVES FROM CAKES OF PLANTS OF THE GENUS THEOBROMA, AS WELL AS COMPOSITION AND USE OF SAID EXTRACT | Natura Cosméticos S.A. (BR) | 2011-10-12 | — | — | EP | disclosed |
| US-20110206739-A1 | COMPOSITIONS AND METHODS FOR THE PREPARATION OF NANOEMULSIONS | UNIVERSITY OF MASSACHUSETTS (US) | 2011-08-25 | — | — | US | disclosed |
| EP-2271314-A2 | COMPOSITIONS AND METHODS FOR THE PREPARATION OF NANOEMULSIONS | University of Massachusetts (US) | 2011-01-12 | — | — | EP | disclosed |
| US-20090208541-A1 | Oil-In-Water Nanoemulsion, A Cosmetic Composition And A Cosmetic Product Comprising It, A Process For Preparing Said Nanoemulsion | NATURA COSMETICOS S.A. (BR) | 2009-08-20 | — | — | US | disclosed |
| US-20090023628-A1 | Cosmetic Composition and a Process for Preparing This Cosmetic Composition and a Cosmetic Product | NATURA COSMETICOS S.A. (BR) | 2009-01-22 | — | — | US | disclosed |
| US-20080075677-A1 | Antioxidant Complex and a Cosmetic and Pharmaceutical Composition Comprising Said Complex | NATURA COSMETICOS S.A. (BR) | 2008-03-27 | — | — | US | disclosed |
| US-20070269389-A1 | Base Composition for Preparing Multi-Functional Formulations for Care and Protection of the Skin and Hair | NATURA COSMETICOS S.A. (BR) | 2007-11-22 | — | — | US | disclosed |
| EP-1817045-A2 | AN OIL-IN-WATER NANOEMULSION, A COSMETIC COMPOSITION AND A COSMETIC PRODUCT COMPRISING IT, A PROCESS FOR PREPARING SAID NANOEMULSION | Natura Cosméticos S.A. (BR) | 2007-08-15 | — | — | EP | disclosed |
| EP-1793793-A1 | AN ANTIOXIDANT COMPLEX AND A COSMETIC AND PHARMACEUTICAL COMPOSITION COMPRISING SAID COMPLEX | Natura Cosméticos S.A. (BR) | 2007-06-13 | — | — | EP | disclosed |
| EP-1722859-A1 | A BASE COMPOSITION FOR PREPARING MULTI-FUNCTIONAL FORMULATIONS FOR CARE AND PROTECTION OF THE SKIN AND HAIR | Natura Cosméticos S.A. (BR) | 2006-11-22 | — | — | EP | disclosed |
| WO-2006045170-A2 | AN OIL-IN-WATER NANOEMULSION, A COSMETIC COMPOSITION AND A COSMETIC PRODUCT COMPRISING IT, A PROCESS FOR PREPARING SAID NANOEMULSION | Natura Cosméticos S.A. (BR) | 2006-05-04 | — | — | WO | disclosed |
| WO-2006032122-A1 | AN ANTIOXIDANT COMPLEX AND A COSMETIC AND PHARMACEUTICAL COMPOSITION COMPRISING SAID COMPLEX | Natura Cosméticos S.A. (BR) | 2006-03-30 | — | — | WO | disclosed |
| WO-2005060923-A1 | A BASE COMPOSITION FOR PREPARING MULTI-FUNCTIONAL FORMULATIONS FOR CARE AND PROTECTION OF THE SKIN AND HAIR | Natura Cosméticos S.A. (BR) | 2005-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172326-A1 | Moisturizing Mixture, Cosmetic And/Or Pharmaceutical Compositions Containing The Moisturizing Mixture, Use Of The Moisturizing Mixture, And Cosmetic Method | NHERF1, NPFFR1, CUTA | CES2 3915/4885CES1 3606/4885MEN1 464/4885 |
| US-20120022085-A1 | PROCESS FOR OBTAINING EXTRACTS CONTAINING METHYLXANTHINE DERIVATIVES FROM CAKES OF PLANTS OF THE GENUS THEOBROMA, AS WELL AS COMPOSITION AND USE OF SAID EXTRACT | CEL, LIPA, LIPE | CES2 89/4885CES1 23/4885MEN1 592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.