Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 11/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4108419 | 0.91 | CRHR1 (0.33) | CRHR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4091836 | 0.90 | SLC40A1 (0.33) | CRHR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4096878 | 0.87 | SLC40A1 (0.35) | PDE4APDE4BPDE4CPDE4DSLC40A1 | |
| SCHEMBL4090226 | 0.85 | METAP2 (0.37) | CRHR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4708043 | 0.78 | CRHR1 (0.32) | CRHR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4710336 | 0.78 | SLC40A1 (0.34) | CRHR1SLC40A1NFKBIARELANR1H2 | |
| SCHEMBL4101998 | 0.72 | HPGD (0.35) | CRHR1NR1H2NR1H3 | |
| SCHEMBL4107196 | 0.71 | RXFP1 (0.38) | CRHR1NR1H2NR1H3 | |
| SCHEMBL4107183 | 0.70 | CRHR1 (0.35) | CRHR1NR1H2NR1H3 | |
| SCHEMBL4095952 | 0.70 | CRHR1 (0.41) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090234117-A1 | Pyrazolopyrimidine Derivative | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234117-A1 | Pyrazolopyrimidine Derivative | MC2R, CRHR1, AVPR2 | CRHR1 2/4885PDE4A 985/4885PDE4B 1164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.