Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 5/20 | 0.34 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4091836 | 0.79 | SLC40A1 (0.33) | SLC40A1NFKBIARELAKDM4EL3MBTL1 | |
| SCHEMBL4708043 | 0.79 | CRHR1 (0.32) | SLC40A1NFKBIARELAKDM4EL3MBTL1 | |
| SCHEMBL4108419 | 0.78 | CRHR1 (0.33) | SLC40A1NFKBIARELAKDM4EL3MBTL1 | |
| SCHEMBL4090226 | 0.78 | METAP2 (0.37) | SLC40A1NFKBIARELANR1H2NR1H3 | |
| SCHEMBL4105491 | 0.78 | CRHR1 (0.35) | SLC40A1NFKBIARELAKDM4EL3MBTL1 | |
| SCHEMBL4096878 | 0.75 | SLC40A1 (0.35) | SLC40A1NFKBIARELAKDM4EL3MBTL1 | |
| SCHEMBL4101998 | 0.67 | HPGD (0.35) | NR1H2NR1H3CRHR1 | |
| SCHEMBL4107196 | 0.65 | RXFP1 (0.38) | NR1H2NR1H3CRHR1 | |
| SCHEMBL4107183 | 0.64 | CRHR1 (0.35) | NR1H2NR1H3CRHR1 | |
| SCHEMBL4102274 | 0.64 | NLRP3 (0.33) | NR1H2NR1H3CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1903045-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-03-26 | — | — | EP | disclosed |