Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4090226 | 0.84 | METAP2 (0.37) | CRHR1SLC40A1NFKBIARELANR1H2 | |
| SCHEMBL4710336 | 0.79 | SLC40A1 (0.34) | CRHR1KDM4EL3MBTL1SLC40A1NFKBIA | |
| SCHEMBL4105491 | 0.78 | CRHR1 (0.35) | CRHR1KDM4EL3MBTL1SLC40A1NFKBIA | |
| SCHEMBL4108419 | 0.77 | CRHR1 (0.33) | CRHR1KDM4EL3MBTL1SLC40A1PDE2A | |
| SCHEMBL4091836 | 0.77 | SLC40A1 (0.33) | CRHR1KDM4EL3MBTL1SLC40A1NFKBIA | |
| SCHEMBL4096878 | 0.74 | SLC40A1 (0.35) | KDM4EL3MBTL1SLC40A1NFKBIARELA | |
| SCHEMBL4101998 | 0.71 | HPGD (0.35) | CRHR1NR1H2NR1H3 | |
| SCHEMBL4107196 | 0.70 | RXFP1 (0.38) | CRHR1PDE2APDE10ANR1H2NR1H3 | |
| SCHEMBL4089957 | 0.70 | MET (0.32) | NR1H2NR1H3 | |
| SCHEMBL4107183 | 0.70 | CRHR1 (0.35) | CRHR1PDE2APDE10ANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1903045-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-03-26 | — | — | EP | disclosed |