Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29168432 | 0.84 | LMNA (0.71) | LMNASIGMAR1KMT2ACHRM3KDM4E | |
| SCHEMBL27782053 | 0.80 | ALDH1A1 (0.56) | LMNAKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL593284 | 0.79 | LMNA (0.96) | LMNASIGMAR1KMT2AKDM4EMEN1 | |
| SCHEMBL1259602 | 0.79 | SIGMAR1 (0.71) | SIGMAR1BRD4KMT2AMEN1CXCR4 | |
| SCHEMBL21961925 | 0.79 | SIGMAR1 (0.71) | SIGMAR1BRD4KMT2AMEN1CXCR4 | |
| Hydrochloric Acid SCHEMBL2924720 | 0.78 | LMNA (1.00) | LMNASIGMAR1KMT2AKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL7417639 | 0.78 | LMNA (1.00) | LMNASIGMAR1KMT2AKDM4EMEN1 | |
| Bromide SCHEMBL1259195 | 0.77 | SIGMAR1 (0.69) | SIGMAR1BRD4KMT2AMEN1ALDH1A1 | |
| SCHEMBL593734 | 0.76 | SIGMAR1 (0.62) | LMNASIGMAR1KMT2ACHRM3KDM4E | |
| SCHEMBL12320535 | 0.76 | SIGMAR1 (0.62) | LMNASIGMAR1BRD4KMT2ACHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090062294-A1 | HETEROARYL-SUBSTITUTED UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062294-A1 | HETEROARYL-SUBSTITUTED UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, GPR119 | LMNA 2277/4885SIGMAR1 1261/4885BRD4 560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.