Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3088205 | 0.91 | ADORA3 (0.55) | ADORA3ADORA2AADORA2BADORA1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL4114413 | 0.82 | ADORA3 (0.72) | ADORA3ADORA2AADORA2BADORA1SMN1; SMN2 | |
| SCHEMBL16238753 | 0.78 | LMNA (0.48) | SMN1; SMN2NPC1RAB9ALMNATP53 | |
| SCHEMBL17960860 | 0.77 | ADORA3 (0.54) | ADORA3ADORA2AADORA2BADORA1SMN1; SMN2 | |
| SCHEMBL9108540 | 0.76 | HSD17B1 (0.46) | ADORA3ADORA2AADORA2BADORA1SMN1; SMN2 | |
| SCHEMBL11883602 | 0.75 | CYP19A1 (0.58) | SMN1; SMN2LMNATP53HTTMAPT | |
| SCHEMBL2564546 | 0.74 | ADORA3 (0.55) | ADORA3ADORA2AADORA2BADORA1SMN1; SMN2 | |
| SCHEMBL9107820 | 0.72 | ADORA3 (0.58) | ADORA3SMN1; SMN2TP53KMT2AMAPT | |
| Trifluoroacetic Acid SCHEMBL29379876 | 0.72 | HDAC6 (0.52) | ADORA2AL3MBTL1HDAC4HDAC1HDAC6 | |
| Trifluoroacetic Acid SCHEMBL6926839 | 0.71 | MKNK1 (0.59) | SMN1; SMN2NPC1RAB9ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090062294-A1 | HETEROARYL-SUBSTITUTED UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062294-A1 | HETEROARYL-SUBSTITUTED UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, GPR119 | ADORA3 766/4885ADORA2A 484/4885ADORA2B 436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.