Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL375857 | 0.82 | CYP1A2 (0.56) | TRPA1SRRCYP1A2ALPIPKM | |
| SCHEMBL16476537 | 0.82 | CYP1A2 (0.56) | TRPA1SRRCYP1A2ALPIPKM | |
| SCHEMBL7046944 | 0.81 | ALDH1A1 (0.55) | SRRCYP1A2 | |
| SCHEMBL4219709 | 0.81 | ALDH1A1 (0.55) | SRRCYP1A2 | |
| SCHEMBL262278 | 0.81 | ALDH1A1 (0.55) | SRRCYP1A2 | |
| SCHEMBL6284464 | 0.80 | MMP8 (0.59) | TRPA1CYP1A2PKMPOLBPPARG | |
| SCHEMBL1245765 | 0.80 | MMP8 (0.59) | TRPA1CYP1A2PKMPOLBPPARG | |
| SCHEMBL1785293 | 0.80 | MMP8 (0.59) | TRPA1CYP1A2PKMPOLBPPARG | |
| SCHEMBL821837 | 0.79 | CYP1A2 (0.46) | TRPA1SRRCYP1A2ALPIPKM | |
| SCHEMBL1637392 | 0.78 | THRB (0.47) | TRPA1SRRCYP1A2ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030083380-A1 | Method of using hydroxycarboxylic acids or related compounds for treating skin changes asociated with intrinsic and extrinsic aging | YU RUEY J (US) | 2003-05-01 | — | — | US | claimed |
| US-5886041-A | SKIN DISORDERS | TRISTRATA TECHNOLOGY, INC. (US) | 1999-03-23 | — | — | US | claimed |
| EP-0413528-B1 | Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use | YU RUEY J (US) | 1995-11-15 | — | — | EP | claimed |
| EP-0671162-A2 | Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use | Yu, Ruey J., Dr. (US) | 1995-09-13 | — | — | EP | claimed |
| US-5091171-A | Skin disorders | IGI, INC. | 1992-02-25 | — | — | US | claimed |
| EP-0413528-A1 | Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use | Yu, Ruey J., Dr. (US) | 1991-02-20 | — | — | EP | claimed |
| US-20090105196-A1 | USE OF CREATINE COMPOUNDS TO TREAT DERMATITIS | AVICENA GROUP, INC. | 2009-04-23 | — | — | US | disclosed |
| WO-2009002913-A1 | USE OF CREATINE COMPOUNDS TO TREAT DERMATITIS | AVICENA GROUP, INC. (US) | 2008-12-31 | — | — | WO | disclosed |
| EP-1207846-B1 | TOWELETTE PRODUCT | UNILEVER PLC (GB) | 2006-10-18 | — | — | EP | disclosed |
| EP-1161518-B1 | TOWELETTE PRODUCT | UNILEVER PLC (GB) | 2006-05-31 | — | — | EP | disclosed |
| US-6767924-B2 | COMPRISES 2-KETOETHANOIC ACID FOR COSMETIC CONDITIONS AND DERMATOLOGIC DISORDERS | TRISTRATA TECHNOLOGY, INC. | 2004-07-27 | — | — | US | disclosed |
| US-20030083380-A1 | Method of using hydroxycarboxylic acids or related compounds for treating skin changes asociated with intrinsic and extrinsic aging | YU RUEY J (US) | 2003-05-01 | — | — | US | disclosed |
| US-20030044362-A1 | Method and product for skin lightening | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2003-03-06 | — | — | US | disclosed |
| US-5643961-A | TREATMENT OF SKIN WITH COSMETICS | TRISTRATA TECHNOLOGY, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5637615-A | ANTIAGING AGENT | TRISTRATA TECHNOLOGY, INC. (US) | 1997-06-10 | — | — | US | disclosed |
| EP-0413528-B1 | Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use | YU RUEY J (US) | 1995-11-15 | — | — | EP | disclosed |
| EP-0671162-A2 | Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use | Yu, Ruey J., Dr. (US) | 1995-09-13 | — | — | EP | disclosed |
| US-5385938-A | application of mixtures containing hydroxyacetic acid(or its salts) to skin | IGI, INC. | 1995-01-31 | — | — | US | disclosed |
| US-5091171-A | Skin disorders | IGI, INC. | 1992-02-25 | — | — | US | disclosed |
| EP-0413528-A1 | Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use | Yu, Ruey J., Dr. (US) | 1991-02-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105196-A1 | USE OF CREATINE COMPOUNDS TO TREAT DERMATITIS | CKMT1A; CKMT1B, CRAT, LRAT | TRPA1 3478/4885SRR 19/4885CYP1A2 1666/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.