Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SRR | Q9GZT4 | 3/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL375857 | 1.00 | CYP1A2 (0.56) | CYP1A2SMN1; SMN2PKMCYP2D6NPSR1 | |
| SCHEMBL2258396 | 0.83 | LMNA (0.56) | CYP1A2SMN1; SMN2PKMCYP2D6NPSR1 | |
| SCHEMBL28108510 | 0.83 | CYP1A2 (0.48) | CYP1A2SMN1; SMN2PKMCYP2D6NPSR1 | |
| SCHEMBL4116706 | 0.82 | TRPA1 (0.47) | CYP1A2PKMSRRTRPA1ALPI | |
| Solriamfetol SCHEMBL2739637 | 0.82 | PKM (0.56) | CYP1A2SMN1; SMN2PKMCYP2D6NPSR1 | |
| Solriamfetol SCHEMBL30929349 | 0.82 | PKM (0.56) | CYP1A2SMN1; SMN2PKMCYP2D6NPSR1 | |
| Solriamfetol SCHEMBL42526 | 0.82 | PKM (0.56) | CYP1A2SMN1; SMN2PKMCYP2D6NPSR1 | |
| Solriamfetol SCHEMBL42525 | 0.82 | PKM (0.56) | CYP1A2SMN1; SMN2PKMCYP2D6NPSR1 | |
| Solriamfetol SCHEMBL30929348 | 0.82 | PKM (0.56) | CYP1A2SMN1; SMN2PKMCYP2D6NPSR1 | |
| SCHEMBL28625596 | 0.81 | CA1 (0.58) | CYP1A2SMN1; SMN2PKMCYP2D6NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496228-B1 | METHODS FOR TREATING ATTENTION-DEFICIT/HYPERACTIVITY DISORDER | SK BIOPHARMACEUTICALS CO LTD (KR) | 2014-01-15 | — | — | EP | disclosed |