SCHEMBL1245765

SCHEMBL1245765

CCOC(=O)C(O)Cc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 2/20 0.59
CYP1A2 P05177 2/20 0.54
CYP2C9 P11712 1/20 0.54
HIF1A Q16665 1/20 0.54
ALDH1A1 P00352 2/20 0.52
TP53 P04637 1/20 0.52
NPY1R P25929 1/20 0.51
NPY2R P49146 1/20 0.51
PIN1 Q13526 1/20 0.50
PKM P14618 1/20 0.49
EPHX2 P34913 1/20 0.49
PPARG P37231 1/20 0.49
MEN1 O00255 1/20 0.49
NPC1 O15118 1/20 0.49
KMT2A Q03164 1/20 0.49
L3MBTL1 Q9Y468 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
LMNA P02545 2/20 0.48
POLB P06746 1/20 0.47
HSD17B10 Q99714 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6284464 1.00 MMP8 (0.59) MMP8CYP1A2CYP2C9HIF1AALDH1A1
SCHEMBL1785293 1.00 MMP8 (0.59) MMP8CYP1A2CYP2C9HIF1AALDH1A1
SCHEMBL5390701 0.93 MMP8 (0.54) MMP8CYP1A2CYP2C9HIF1AALDH1A1
SCHEMBL5375675 0.87 L3MBTL1 (0.65) ALDH1A1PPARGL3MBTL1LMNA
SCHEMBL1596779 0.87 L3MBTL1 (0.65) ALDH1A1PPARGL3MBTL1LMNA
SCHEMBL4756342 0.87 L3MBTL1 (0.65) ALDH1A1PPARGL3MBTL1LMNA
SCHEMBL5810826 0.86 LMNA (0.51) MMP8CYP1A2ALDH1A1PPARGNPC1
SCHEMBL14305548 0.85 NPY1R (0.56) MMP8CYP1A2CYP2C9HIF1AALDH1A1
SCHEMBL5385979 0.84 ESR1 (0.50) MMP8CYP1A2CYP2C9HIF1A
SCHEMBL5100527 0.84 ESR1 (0.50) MMP8CYP1A2CYP2C9HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109134765-A A kind of polyisobutene and the graft copolymer of polyisoprene and preparation method thereof 北京化工大学 2019-01-04 CN claimed
CN-106366980-A Corrosion-resistant anaerobic adhesive 无锡万能胶粘剂有限公司 2017-02-01 CN claimed
US-8592621-B2 Precursor compounds of sweet taste receptor antagonists for the prevention or treatment of disease SYMRISE AG (DE) 2013-11-26 US claimed
US-20110045069-A1 PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE SYMRISE GMBH CO. KG (DE) 2011-02-24 US claimed
WO-2006119283-A2 ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE YU RUEY J (US) 2006-11-09 WO claimed
US-20060251597-A1 ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE YU RUEY J 2006-11-09 US claimed
CN-1379748-A Process for preparing optically active alpha-hydroxy acids and derivatives thereof SCINOPHARM SINGAPORE PTE LTD (SG) 2002-11-13 CN claimed
US-20250223263-A1 SELECTIVE INHIBITORS OF NLRP3 INFLAMMASOME NodThera Limited (GB) 2025-07-10 US disclosed
WO-2025132660-A1 METHOD FOR TREATING HUMAN PERSPIRATION, AND ASSOCIATED COMPOSITION L'OREAL (FR) 2025-06-26 WO disclosed
US-12247011-B2 Selective inhibitors of NLRP3 inflammasome NodThera Limited (GB) 2025-03-11 US disclosed
US-20250009621-A1 ANHYDROUS HAIR TREATMENT COMPOSITION COMPRISING ALPHA HYDROXY ACID ESTER L'OREAL (FR) 2025-01-09 US disclosed
WO-2025006991-A1 ANHYDROUS HAIR TREATMENT COMPOSITION COMPRISING ALPHA HYDROXY ACID ESTER L'OREAL (FR) 2025-01-02 WO disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
US-5342981-A Substantially isomerically pure hexane or hexene compounds ABBOTT LABORATORIES (US) 1994-08-30 US disclosed
US-5229518-A Isomerically pure 2-piperidone compounds ABBOTT LABORATORIES (US) 1993-07-20 US disclosed
CN-1071423-A BICYCLIC CARBOXYLIC ACID DERIVATIVES HOFFMANN LA ROCHE (CH) 1993-04-28 CN disclosed
EP-0413368-A1 Bread aroma, production thereof, and use of the same for the aromatisation of foodstuffs and delicacies FÜRSTLICHE BRAUEREI THURN UND TAXIS REGENSBURG GMBH (DE) 1991-02-20 EP disclosed
EP-0048159-A2 Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents UNIVERSITY OF MIAMI (US) 1982-03-24 EP disclosed
US-4179500-A 1,4-Dihydropyridine-sugar derivatives, and their use as medicaments BAYER AKTIENGESELLSCHAFT (DE) 1979-12-18 US disclosed
US-4064236-A Peptide carbazates and pharmaceutical composition MERCK & CO., INC. (US) 1977-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12247011-B2 Selective inhibitors of NLRP3 inflammasome NLRP3, NOD1, NLRP1 MMP8 301/4885CYP1A2 2468/4885CYP2C9 2910/4885
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 MMP8 4473/4885CYP1A2 4564/4885CYP2C9 4567/4885
US-20250223263-A1 SELECTIVE INHIBITORS OF NLRP3 INFLAMMASOME NLRP3, NOD1, NLRP1 MMP8 301/4885CYP1A2 2468/4885CYP2C9 2910/4885
US-20250009621-A1 ANHYDROUS HAIR TREATMENT COMPOSITION COMPRISING ALPHA HYDROXY ACID ESTER EBP, ADH1A, ADH1C MMP8 3459/4885CYP1A2 1563/4885CYP2C9 2101/4885
US-20110045069-A1 PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE TAS1R2, TAS2R5, TAS2R1 MMP8 4326/4885CYP1A2 3575/4885CYP2C9 4382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.