Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | PRCP | P42785 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14279692 | 0.87 | SLC6A4 (0.50) | SIGMAR1GRIN2DGRIN3BCYP2B6SLC6A2 | |
| SCHEMBL14279640 | 0.86 | SLC6A4 (0.56) | SIGMAR1GRIN2DGRIN3BCYP2B6SLC6A2 | |
| SCHEMBL2335867 | 0.84 | GRIN1 (0.70) | SIGMAR1GRIN2DGRIN3BCYP2B6SLC6A2 | |
| SCHEMBL4120887 | 0.84 | SLC6A9 (0.39) | SLC6A2SLC6A3GRIN1KCNH2GRIN2A | |
| SCHEMBL6023084 | 0.83 | GRIN1 (0.73) | SIGMAR1GRIN2DGRIN3BCYP2B6SLC6A2 | |
| Hydrochloric Acid SCHEMBL2333446 | 0.83 | OPRM1 (0.71) | SIGMAR1GRIN2DGRIN3BCYP2B6SLC6A2 | |
| SCHEMBL4120082 | 0.82 | OPRM1 (0.42) | SLC6A2SLC6A4SLC6A3OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL7751676 | 0.81 | OPRM1 (0.74) | SIGMAR1GRIN2DGRIN3BCYP2B6SLC6A2 | |
| Hydrochloric Acid SCHEMBL2329545 | 0.81 | OPRM1 (0.41) | SLC6A2SLC6A4SLC6A3OPRM1OPRD1 | |
| SCHEMBL10261142 | 0.80 | SIGMAR1 (0.58) | SIGMAR1GRIN2DGRIN3BCYP2B6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | SIGMAR1 1349/4885GRIN2D 2928/4885GRIN3B 4336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.