Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 6/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4124756 | 0.84 | SIGMAR1 (0.50) | SLC6A9OPRM1KCNH2GRIN1GRIN2A | |
| SCHEMBL4120082 | 0.82 | OPRM1 (0.42) | SLC6A9OPRM1CYP2D6SLC6A3USP2 | |
| SCHEMBL23293520 | 0.82 | SLC6A9 (0.43) | SLC6A9OPRM1KCNH2GRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL2329545 | 0.81 | OPRM1 (0.41) | SLC6A9OPRM1CYP2D6SLC6A3USP2 | |
| SCHEMBL30330148 | 0.79 | SLC6A9 (0.47) | SLC6A9OPRM1KCNH2GRIN1GRIN2A | |
| SCHEMBL4283594 | 0.74 | SMN1; SMN2 (0.47) | SLC6A9OPRM1SMN1; SMN2CYP2D6NPC1 | |
| Methylpiperazine SCHEMBL28078163 | 0.73 | SIGMAR1 (0.47) | KCNH2SMN1; SMN2CYP2D6NPC1LMNA | |
| Methylpiperazine SCHEMBL28021840 | 0.72 | SIGMAR1 (0.46) | KCNH2SMN1; SMN2CYP2D6NPC1LMNA | |
| SCHEMBL19869969 | 0.71 | ALDH1A1 (0.44) | OPRM1KCNH2DUSP3PTPN5PTPN11 | |
| SCHEMBL14279692 | 0.71 | SLC6A4 (0.50) | SLC6A9OPRM1KCNH2GRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
| US-20090253669-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253669-A1 | Substituted Sulfonamide Compounds | SULT2A1, STS, SULT1A1 | SLC6A9 600/4885OPRM1 2798/4885KCNH2 1264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.