Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20993378 | 0.90 | KMT2A (0.47) | KMT2AMAPK1CYP26A1TDP1TACR1 | |
| SCHEMBL13742987 | 0.87 | ALDH1A1 (0.48) | KMT2AMAPK1TDP1TACR1ALDH1A1 | |
| SCHEMBL4147001 | 0.86 | CYP26A1 (0.51) | KMT2AMAPK1CYP26A1ALDH1A1MEN1 | |
| SCHEMBL6092152 | 0.84 | JAK3 (0.47) | KMT2ACYP26A1MAPT | |
| SCHEMBL7274758 | 0.83 | CYP3A4 (0.49) | KMT2AALDH1A1TSHRMEN1 | |
| SCHEMBL22982779 | 0.83 | CYP3A4 (0.49) | KMT2AALDH1A1TSHRMEN1 | |
| SCHEMBL20743185 | 0.83 | GAA (0.45) | KMT2ATACR1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL4142019 | 0.82 | RECQL (0.56) | KMT2A | |
| SCHEMBL8382243 | 0.81 | FAAH (0.46) | KMT2AMAPK1TDP1ALDH1A1MAPT | |
| SCHEMBL362624 | 0.81 | TDP1 (0.56) | KMT2ATDP1TACR1L3MBTL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209578-A1 | CHEMICAL COMPOUNDS | PFIZER INC | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209578-A1 | CHEMICAL COMPOUNDS | CCR5, CXCR3, CXCR1 | KMT2A 3350/4885MAPK1 1254/4885CYP26A1 917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.