Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 12/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573959 | 0.84 | RECQL (0.59) | RECQLKMT2ASMN1; SMN2LMNACCR5 | |
| SCHEMBL1573757 | 0.84 | RECQL (0.59) | RECQLKMT2ASMN1; SMN2LMNACCR5 | |
| SCHEMBL4125738 | 0.82 | KMT2A (0.48) | KMT2A | |
| SCHEMBL4130312 | 0.81 | RECQL (0.62) | RECQLKMT2ASMN1; SMN2LMNACCR5 | |
| SCHEMBL20993378 | 0.81 | KMT2A (0.47) | KMT2A | |
| SCHEMBL4138087 | 0.81 | SMN1; SMN2 (0.63) | RECQLKMT2ASMN1; SMN2LMNACCR5 | |
| SCHEMBL9830370 | 0.81 | SMN1; SMN2 (0.63) | RECQLKMT2ASMN1; SMN2LMNACCR5 | |
| SCHEMBL13743002 | 0.81 | RECQL (0.56) | RECQLKMT2ASMN1; SMN2LMNACCR5 | |
| SCHEMBL5424938 | 0.78 | LMNA (0.61) | RECQLKMT2ASMN1; SMN2LMNACCR5 | |
| SCHEMBL22904618 | 0.78 | SMN1; SMN2 (0.55) | RECQLKMT2ASMN1; SMN2LMNACCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209578-A1 | CHEMICAL COMPOUNDS | PFIZER INC | 2009-08-20 | — | — | US | disclosed |
| US-20090209578-A1 | CHEMICAL COMPOUNDS | PFIZER INC | 2009-08-20 | — | — | US | disclosed |
| US-20090209578-A1 | CHEMICAL COMPOUNDS | PFIZER INC | 2009-08-20 | — | — | US | disclosed |
| WO-2007066201-A2 | CHEMICAL COMPOUNDS | PFIZER LIMITED (GB) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209578-A1 | CHEMICAL COMPOUNDS | CCR5, CXCR3, CXCR1 | RECQL 1937/4885KMT2A 3350/4885SMN1; SMN2 4870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.