Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 6/20 | 0.38 |
| ▸ | SLC16A1 | P53985 | 5/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4123658 | 0.91 | TAS2R14 (0.35) | NAMPTKEAP1NFE2L2KDM4EHTT | |
| SCHEMBL4125769 | 0.89 | SLC16A3 (0.39) | SLC16A3SLC16A1CNR1HTTNOX4 | |
| SCHEMBL4131429 | 0.89 | KEAP1 (0.36) | NAMPTKEAP1NFE2L2LMNAMAPT | |
| SCHEMBL4131198 | 0.89 | NAMPT (0.39) | NAMPTSLC16A3SLC16A1KDM4ELMNA | |
| SCHEMBL4135860 | 0.88 | SLC16A3 (0.37) | NAMPTSLC16A3SLC16A1MEN1KMT2A | |
| SCHEMBL4126819 | 0.88 | CNR1 (0.38) | NAMPTSLC16A3SLC16A1CNR1HSD11B1 | |
| SCHEMBL4135426 | 0.87 | NAMPT (0.36) | NAMPTKEAP1NFE2L2HTTGPBAR1 | |
| SCHEMBL3702449 | 0.87 | ALDH1A1 (0.44) | NAMPTSLC16A3SLC16A1MEN1MAPT | |
| SCHEMBL4130995 | 0.85 | NAMPT (0.36) | NAMPT | |
| SCHEMBL4125804 | 0.85 | NAMPT (0.36) | NAMPTKEAP1NFE2L2MAPTGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-B1 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2014-12-31 | — | — | EP | disclosed |
| US-20090156642-A1 | 5-Membered heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156642-A1 | 5-Membered heterocyclic compound | CEL, PGA5, COG5 | NAMPT 2129/4885SLC16A3 2809/4885SLC16A1 2925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.