Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyruvate SCHEMBL7929357 | 0.96 | — | — | |
| Succinic Acid SCHEMBL6340677 | 0.86 | LMNA (0.34) | KDM6BKDM5CEGLN1PHF8KDM2A | |
| Succinic Acid SCHEMBL15323172 | 0.82 | EGLN1 (0.43) | KDM6BKDM5CEGLN1PHF8KDM2A | |
| Succinic Acid SCHEMBL9065587 | 0.80 | LMNA (0.44) | KDM6BKDM5CEGLN1PHF8KDM2A | |
| Propionic Acid SCHEMBL8734266 | 0.77 | FFAR3 (0.42) | CYP1A2 | |
| Lactic Acid SCHEMBL4133671 | 0.77 | ALDH1A1 (0.41) | KDM6BKDM5CEGLN1PHF8KDM2A | |
| Butyric Acid SCHEMBL10578465 | 0.76 | FFAR3 (0.52) | CYP1A2 | |
| Butane SCHEMBL7832973 | 0.75 | FFAR3 (0.44) | KDM6BKDM5CEGLN1PHF8KDM2A | |
| SCHEMBL4377797 | 0.75 | LMNA (0.47) | KDM6BKDM5CEGLN1PHF8KDM2A | |
| SCHEMBL935213 | 0.73 | EGLN1 (0.45) | KDM6BKDM5CEGLN1PHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041293-A2 | ETHANOL PRODUCTION IN NON-RECOMBINANT HOSTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008018930-A2 | ETHANOL PRODUCTION IN NON-RECOMBINANT HOSTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2008-02-14 | — | — | WO | disclosed |