Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7781759 | 0.83 | ENPP2 (0.38) | ENPP2KDM4EHPGDTDP1MMP3 | |
| SCHEMBL4135418 | 0.77 | TTR (0.37) | SLC6A4ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL2308 | 0.77 | IDO1 (0.52) | ENPP2KDM4EHPGDTDP1LMNA | |
| SCHEMBL29609180 | 0.77 | IDO1 (0.52) | ENPP2KDM4EHPGDTDP1LMNA | |
| SCHEMBL6936444 | 0.76 | MAPT (0.36) | ENPP2HPGDNPC1MAPTLMNA | |
| SCHEMBL24108441 | 0.76 | TRPV4 (0.52) | ENPP2ARIDO1 | |
| SCHEMBL7202582 | 0.76 | MAPT (0.43) | ENPP2KDM4ENPC1MAPTTDP1 | |
| SCHEMBL30336953 | 0.76 | MAPT (0.43) | ENPP2KDM4ENPC1MAPTTDP1 | |
| SCHEMBL6198392 | 0.76 | RECQL (0.38) | HPGDNPC1MAPTHTTSLC6A4 | |
| SCHEMBL4711611 | 0.72 | CYP3A4 (0.61) | ENPP2KDM4EHPGDNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088584-A1 | PROCESS FOR PREPARING 3, 4-DISUBSTITUTED PHENYLACETIC ACIDS AND NOVEL INTERMEDIATES | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2009-04-02 | — | — | US | disclosed |
| EP-1986995-A1 | PROCESS FOR PREPARING 3, 4-DISUBSTITUTED PHENYLACETIC ACIDS AND NOVEL INTERMEDIATES | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007096034-A1 | PROCESS FOR PREPARING 3, 4-DISUBSTITUTED PHENYLACETIC ACIDS AND NOVEL INTERMEDIATES | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2007-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088584-A1 | PROCESS FOR PREPARING 3, 4-DISUBSTITUTED PHENYLACETIC ACIDS AND NOVEL INTERMEDIATES | PAH, CTRC, DDC | ENPP2 1019/4885KDM4E 3261/4885HPGD 3894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.