Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786392 | 0.83 | TTR (0.33) | TTRSLC6A4ALDH1A1TSHR | |
| SCHEMBL6198392 | 0.82 | RECQL (0.38) | TTRSLC6A4IDO1ALDH1A1SLC6A2 | |
| SCHEMBL11868272 | 0.79 | CYP3A4 (0.39) | TTRSLC6A4ALDH1A1CYP3A4TSHR | |
| SCHEMBL4128552 | 0.77 | ENPP2 (0.35) | SLC6A4IDO1MEN1KMT2AALDH1A1 | |
| SCHEMBL1552039 | 0.77 | PNMT (0.38) | SLC6A4PNMTCYP3A4SLC6A2SLC6A3 | |
| SCHEMBL1552037 | 0.77 | PNMT (0.38) | SLC6A4PNMTCYP3A4SLC6A2SLC6A3 | |
| SCHEMBL2162178 | 0.76 | CA2 (0.59) | MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL14355057 | 0.76 | CA2 (0.42) | MEN1KMT2ATSHR | |
| SCHEMBL13687739 | 0.76 | CYP3A4 (0.44) | SLC6A4PNMTCYP3A4TAAR1SLC6A2 | |
| SCHEMBL28803630 | 0.75 | TTR (0.32) | TTRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088584-A1 | PROCESS FOR PREPARING 3, 4-DISUBSTITUTED PHENYLACETIC ACIDS AND NOVEL INTERMEDIATES | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2009-04-02 | — | — | US | disclosed |
| CN-101389602-A | Process for preparing 3, 4-disubstituted phenylacetic acids and novel intermediates | DSM FINE CHEM AUSTRIA GMBH (AT) | 2009-03-18 | — | — | CN | disclosed |
| EP-1986995-A1 | PROCESS FOR PREPARING 3, 4-DISUBSTITUTED PHENYLACETIC ACIDS AND NOVEL INTERMEDIATES | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007096034-A1 | PROCESS FOR PREPARING 3, 4-DISUBSTITUTED PHENYLACETIC ACIDS AND NOVEL INTERMEDIATES | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2007-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088584-A1 | PROCESS FOR PREPARING 3, 4-DISUBSTITUTED PHENYLACETIC ACIDS AND NOVEL INTERMEDIATES | PAH, CTRC, DDC | TTR 1905/4885SLC6A4 266/4885IDO1 878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.