Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.34 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4135836 | 0.85 | HTT (0.37) | ALDH1A1HTTL3MBTL1ATMNAMPT | |
| SCHEMBL4126131 | 0.85 | HTT (0.37) | ALDH1A1HTTL3MBTL1ATMNAMPT | |
| SCHEMBL4137769 | 0.83 | HTT (0.36) | P2RX7ALDH1A1HTTL3MBTL1ATM | |
| SCHEMBL4125767 | 0.82 | NFE2L2 (0.39) | MAPTNAMPTNPC1 | |
| SCHEMBL4131220 | 0.82 | SMO (0.35) | P2RX7ALDH1A1KDM4ESMONAMPT | |
| Fumaric Acid SCHEMBL3704711 | 0.81 | P2RX7 (0.36) | P2RX7ALDH1A1KDM4ESMONAMPT | |
| Fumaric Acid SCHEMBL3704715 | 0.81 | P2RX7 (0.36) | P2RX7ALDH1A1KDM4ESMONAMPT | |
| SCHEMBL3697760 | 0.81 | NR1I2 (0.35) | P2RX7SMONAMPTCYP2C9RAB9A | |
| SCHEMBL476390 | 0.80 | HTT (0.39) | P2RX7ALDH1A1HTTKDM4ENAMPT | |
| SCHEMBL4125774 | 0.80 | SMN1; SMN2 (0.36) | P2RX7ALDH1A1NAMPTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-B1 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2014-12-31 | — | — | EP | disclosed |
| US-20090156642-A1 | 5-Membered heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156642-A1 | 5-Membered heterocyclic compound | CEL, PGA5, COG5 | P2RX7 1303/4885ALDH1A1 1497/4885HTT 3967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.