Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.35 |
| ▸ | SLC16A1 | P53985 | 4/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3697758 | 0.89 | HTR2C (0.43) | SLC16A3SLC16A1NR1I2PTGDR2 | |
| SCHEMBL4126123 | 0.87 | NAMPT (0.35) | SLC16A3SLC16A1ALDH1A1NAMPTKMT2A | |
| SCHEMBL3697762 | 0.86 | KDM4E (0.33) | SMOSLC16A3SLC16A1P2RX7ALDH1A1 | |
| SCHEMBL4135832 | 0.86 | SLC16A3 (0.36) | SLC16A3SLC16A1ALDH1A1NAMPTGAA | |
| SCHEMBL3697997 | 0.86 | HTR2C (0.41) | SLC16A3SLC16A1P2RX7NR1I2 | |
| SCHEMBL4137765 | 0.84 | NAMPT (0.33) | SLC16A3SLC16A1P2RX7ALDH1A1KDM4E | |
| SCHEMBL3697999 | 0.83 | P2RX7 (0.33) | SLC16A3SLC16A1P2RX7ALDH1A1KDM4E | |
| SCHEMBL4125764 | 0.83 | NFE2L2 (0.40) | SLC16A3SLC16A1NAMPT | |
| SCHEMBL4131224 | 0.82 | P2RX7 (0.38) | SMOP2RX7ALDH1A1KDM4ENAMPT | |
| SCHEMBL476388 | 0.82 | PKM (0.38) | KDM4EKMT2APTGDR2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-B1 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2014-12-31 | — | — | EP | disclosed |
| US-20090156642-A1 | 5-Membered heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156642-A1 | 5-Membered heterocyclic compound | CEL, PGA5, COG5 | SMO 2187/4885SLC16A3 2809/4885SLC16A1 2925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.