Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.52 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15342927 | 1.00 | TRPM8 (0.52) | TRPM8ALOX5APHSD11B1SMN1; SMN2TAS1R3 | |
| SCHEMBL29533375 | 1.00 | TRPM8 (0.52) | TRPM8ALOX5APHSD11B1SMN1; SMN2TAS1R3 | |
| SCHEMBL31486820 | 1.00 | TRPM8 (0.52) | TRPM8ALOX5APHSD11B1SMN1; SMN2TAS1R3 | |
| SCHEMBL2628659 | 1.00 | TRPM8 (0.52) | TRPM8ALOX5APHSD11B1SMN1; SMN2TAS1R3 | |
| SCHEMBL529952 | 1.00 | TRPM8 (0.52) | TRPM8ALOX5APHSD11B1SMN1; SMN2TAS1R3 | |
| SCHEMBL31658232 | 1.00 | TRPM8 (0.52) | TRPM8ALOX5APHSD11B1SMN1; SMN2TAS1R3 | |
| SCHEMBL23062653 | 1.00 | TRPM8 (0.52) | TRPM8ALOX5APHSD11B1SMN1; SMN2TAS1R3 | |
| SCHEMBL1159800 | 1.00 | TRPM8 (0.52) | TRPM8ALOX5APHSD11B1SMN1; SMN2TAS1R3 | |
| SCHEMBL29007016 | 1.00 | TRPM8 (0.52) | TRPM8ALOX5APHSD11B1SMN1; SMN2TAS1R3 | |
| SCHEMBL10044144 | 1.00 | TRPM8 (0.52) | TRPM8ALOX5APHSD11B1SMN1; SMN2TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4687503-A1 | FUNCTIONALIZED FLEECE MATERIAL PRODUCTION | Nicoventures Trading Limited (GB) | 2026-02-11 | — | — | EP | claimed |
| US-20250288583-A1 | Treatment of Mucus Hypersecretion | ALTA RESEARCH, LLC | 2025-09-18 | — | — | US | claimed |
| EP-4583718-A1 | FLAVONOID COMPOSITIONS AND USES THEREOF | Firmenich SA (CH) | 2025-07-16 | — | — | EP | claimed |
| WO-2025132323-A1 | COMPOSITIONS COMPRISING A SUNSCREEN ACTIVE AGENT | DSM-FIRMENICH AG (CH) | 2025-06-26 | — | — | WO | claimed |
| CN-120129464-A | Flavonoid compound and application thereof | 弗门尼舍有限公司 | 2025-06-10 | — | — | CN | claimed |
| EP-4251122-B1 | COMPOSITIONS THAT ENHANCE THE COOLING EFFECT | FIRMENICH INCORPORATED (US) | 2025-03-12 | — | — | EP | claimed |
| WO-2024201346-A1 | FUNCTIONALIZED FLEECE MATERIAL PRODUCTION | Nicoventures Trading Limited (GB) | 2024-10-03 | — | — | WO | claimed |
| US-20240238183-A1 | COMPOSITIONS THAT ENHANCE THE COOLING EFFECT | FIRMENICH INCORPORATED (US) | 2024-07-18 | — | — | US | claimed |
| US-20240058238-A1 | COMPOSITIONS THAT ENHANCE THE COOLING EFFECT | FIRMENICH INCORPORATED (US) | 2024-02-22 | — | — | US | claimed |
| CN-116744889-A | Composition for enhancing cooling effect | 弗门尼舍公司 | 2023-09-12 | — | — | CN | claimed |
| WO-2022122903-A1 | COMPOSITIONS COMPRISING (BIO)-ALKANEDIOLS AND COOLING AGENTS | SYMRISE AG (DE) | 2022-06-16 | — | — | WO | claimed |
| EP-3996506-A1 | FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS | Bedoukian Research, Inc. (US) | 2022-05-18 | — | — | EP | claimed |
| EP-3996505-A1 | SYNERGISTIC FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS | Bedoukian Research, Inc. (US) | 2022-05-18 | — | — | EP | claimed |
| US-11174249-B2 | Cooling composition | FIRMENICH SA (CH) | 2021-11-16 | — | — | US | claimed |
| EP-3652171-B1 | COOLING COMPOSITIONS CONTAINING AN AMIDE AND AN ALKYL LACTATE | FIRMENICH & CIE (CH) | 2021-09-08 | — | — | EP | claimed |
| WO-2021071898-A1 | FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS | BEDOUKIAN RESEARCH, INC. (US) | 2021-04-15 | — | — | WO | claimed |
| WO-2021071896-A1 | SYNERGISTIC FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS | BEDOUKIAN RESEARCH, INC. (US) | 2021-04-15 | — | — | WO | claimed |
| US-20200157083-A1 | COOLING COMPOSITION | FIRMENICH SA (CH) | 2020-05-21 | — | — | US | claimed |
| CN-110869365-A | Cooling composition | 弗门尼舍有限公司 | 2020-03-06 | — | — | CN | claimed |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2019-08-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157083-A1 | COOLING COMPOSITION | LDHA, LDHB, ADH1A | TRPM8 1016/4885ALOX5AP 795/4885HSD11B1 443/4885 |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM4, TRPM6 | TRPM8 1/4885ALOX5AP 2637/4885HSD11B1 4283/4885 |
| US-11174249-B2 | Cooling composition | LDHA, LDHB, ADH1A | TRPM8 1016/4885ALOX5AP 795/4885HSD11B1 443/4885 |
| US-20250288583-A1 | Treatment of Mucus Hypersecretion | TRPM8, GPR18, OPRL1 | TRPM8 1/4885ALOX5AP 832/4885HSD11B1 3176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.