Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 2/20 | 0.49 |
| ▸ | CDK2 | P24941 | 2/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM6B | O15054 | 1/20 | 0.47 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.46 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | WNT3A | P56704 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4141946 | 0.81 | PDE4B (0.48) | CCNE1CDK2CDK5MEN1KMT2A | |
| SCHEMBL4141440 | 0.81 | NPC1 (0.50) | RAB9ASMN1; SMN2 | |
| SCHEMBL4144446 | 0.81 | ADORA3 (0.48) | MEN1KMT2AHPGDALDH1A1ADORA3 | |
| Hydrochloric Acid SCHEMBL4144562 | 0.80 | EGLN1 (0.47) | CCNE1CDK2CDK5MEN1KMT2A | |
| SCHEMBL4132392 | 0.80 | MEN1 (0.52) | CCNE1CDK2CDK5MEN1KMT2A | |
| SCHEMBL4132347 | 0.80 | CCNE1 (0.51) | CCNE1CDK2CDK5MEN1KMT2A | |
| SCHEMBL4144040 | 0.80 | LMNA (0.54) | CCNE1CDK2CDK5MEN1KMT2A | |
| SCHEMBL4132373 | 0.76 | ADORA3 (0.47) | MEN1KMT2AHPGDALDH1A1ADORA3 | |
| SCHEMBL4144499 | 0.73 | PDE4B (0.45) | CCNE1CDK2CDK5MEN1KMT2A | |
| SCHEMBL9092418 | 0.73 | BCHE (0.49) | BCHEALDH1A1GALR3HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090005560-A1 | PRODUCTION METHOD OF DIAMINOPYRIMIDINE COMPOUNDS | AJINOMOTO CO. INC (JP) | 2009-01-01 | — | — | US | disclosed |
| EP-2009003-A1 | Production method of diaminopyrimidine compounds | Ajinomoto Co., Inc. (JP) | 2008-12-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005560-A1 | PRODUCTION METHOD OF DIAMINOPYRIMIDINE COMPOUNDS | DPYD, DHPS, UMPS | CCNE1 1745/4885CDK2 286/4885CDK5 461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.