Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.67 |
| ▸ | DRD4 | P21917 | 3/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.62 |
| ▸ | DRD3 | P35462 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 3/20 | 0.60 |
| ▸ | BACE1 | P56817 | 3/20 | 0.60 |
| ▸ | BCHE | P06276 | 2/20 | 0.60 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17610278 | 0.91 | BCHE (0.62) | SIGMAR1DRD4DRD2DRD3KMT2A | |
| SCHEMBL22634135 | 0.88 | SIGMAR1 (0.63) | SIGMAR1DRD4DRD2DRD3KMT2A | |
| SCHEMBL8553564 | 0.87 | DRD4 (0.70) | SIGMAR1DRD4DRD2KMT2AACHE | |
| SCHEMBL2425554 | 0.86 | SIGMAR1 (0.78) | SIGMAR1DRD4DRD2DRD3KMT2A | |
| Hydrochloric Acid SCHEMBL21410212 | 0.84 | SIGMAR1 (0.76) | SIGMAR1DRD4DRD2DRD3KMT2A | |
| SCHEMBL8185713 | 0.83 | CYP2C19 (0.62) | SIGMAR1KMT2ADPP7 | |
| SCHEMBL1934269 | 0.82 | ALDH1A1 (0.58) | DRD4DRD2ACHEBACE1BCHE | |
| SCHEMBL10554681 | 0.82 | DRD4 (0.64) | SIGMAR1DRD4DRD2KMT2AACHE | |
| SCHEMBL19743237 | 0.82 | KCNH2 (0.60) | SIGMAR1DRD4DRD2DRD3KMT2A | |
| SCHEMBL3635817 | 0.81 | KMT2A (0.56) | SIGMAR1DRD4DRD2DRD3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090209578-A1 | CHEMICAL COMPOUNDS | PFIZER INC | 2009-08-20 | — | — | US | disclosed |
| WO-2006136917-A1 | TRIAZOLYLPIPERIDINE DERIVATIVES AND USE THEREOF IN THERAPY | PFIZER LIMITED (GB) | 2006-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209578-A1 | CHEMICAL COMPOUNDS | CCR5, CXCR3, CXCR1 | SIGMAR1 295/4885DRD4 361/4885DRD2 394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.