Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.70 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.64 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.64 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.64 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10554681 | 0.95 | DRD4 (0.64) | DRD4SIGMAR1TMEM97SLC6A12MCHR1 | |
| SCHEMBL694949 | 0.87 | SIGMAR1 (0.82) | DRD4SIGMAR1TMEM97SLC6A12MCHR1 | |
| SCHEMBL4133414 | 0.87 | SIGMAR1 (0.67) | DRD4SIGMAR1ACHEKMT2ADRD2 | |
| SCHEMBL22634135 | 0.84 | SIGMAR1 (0.63) | DRD4SIGMAR1ACHEKMT2AMEN1 | |
| SCHEMBL8786936 | 0.82 | DRD4 (1.00) | DRD4SIGMAR1TMEM97SLC6A12MCHR1 | |
| SCHEMBL7694198 | 0.82 | DRD2 (0.85) | DRD4SIGMAR1TMEM97SLC6A12MCHR1 | |
| SCHEMBL7694199 | 0.82 | DRD2 (0.85) | DRD4SIGMAR1TMEM97SLC6A12MCHR1 | |
| SCHEMBL61848 | 0.82 | TMEM97 (0.83) | DRD4SIGMAR1TMEM97SLC6A12MCHR1 | |
| SCHEMBL4840680 | 0.80 | CCR2 (0.76) | DRD4SIGMAR1TMEM97SLC6A12MCHR1 | |
| SCHEMBL31736417 | 0.80 | MCHR1 (0.77) | DRD4SIGMAR1TMEM97SLC6A12MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |