Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 4/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.32 |
| ▸ | SCD | O00767 | 2/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.30 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.30 |
| ▸ | SMO | Q99835 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4131684 | 0.93 | KCNQ3 (0.34) | KCNQ3KCNQ2HTR2CSLC6A4KCNE1 | |
| SCHEMBL4130715 | 0.92 | KCNQ3 (0.32) | KCNQ3KCNQ2HTR2CSLC6A4KCNE1 | |
| SCHEMBL4125525 | 0.91 | CNR1 (0.35) | KCNQ3KCNQ2HTR2CSLC6A4 | |
| SCHEMBL3703719 | 0.88 | HTR2C (0.43) | HTR2CSLC6A4 | |
| SCHEMBL2838662 | 0.88 | SLC16A3 (0.38) | MEN1KMT2AHTR2CSLC6A4 | |
| SCHEMBL3703723 | 0.87 | KCNQ3 (0.30) | KCNQ3KCNQ2 | |
| SCHEMBL4119113 | 0.86 | ALDH1A1 (0.33) | CDK4CCND1HTR2CSLC6A4 | |
| SCHEMBL4123622 | 0.86 | MDM2 (0.36) | MEN1KMT2AHTR2CSLC6A4 | |
| SCHEMBL4123906 | 0.86 | SPR (0.35) | MEN1KMT2AHTR2CSLC6A4SMO | |
| SCHEMBL4130351 | 0.85 | HTR1A (0.32) | HTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-B1 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2014-12-31 | — | — | EP | disclosed |
| US-20090156642-A1 | 5-Membered heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156642-A1 | 5-Membered heterocyclic compound | CEL, PGA5, COG5 | KCNQ3 4287/4885KCNQ2 3933/4885SCD 782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.