Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL4138396

Cc1cc(C)[o+]c(C)c1.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.41
KCNH2 Q12809 9/20 0.35
ACHE P22303 3/20 0.33
EPAS1 Q99814 1/20 0.33
FFAR4 Q5NUL3 1/20 0.32
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA5A P35218 2/20 0.31
CA9 Q16790 2/20 0.31
CA12 O43570 1/20 0.31
CA3 P07451 1/20 0.31
CA6 P23280 1/20 0.31
CA7 P43166 1/20 0.31
CA5B Q9Y2D0 1/20 0.31
RAPGEF4 Q8WZA2 1/20 0.31
PGK1 P00558 1/20 0.31
PGK2 P07205 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL9279613 0.94 GPR3 (0.39) GPR3KCNH2ACHEEPAS1
Trifluoromethanesulfonic Acid SCHEMBL4297059 0.79 GPR3 (0.33) GPR3
Trifluoromethanesulfonic Acid SCHEMBL4144720 0.79 GPR3 (0.39) GPR3KCNH2ACHEEPAS1CA2
SCHEMBL13243784 0.74
SCHEMBL13243783 0.74
SCHEMBL1078659 0.74
Trifluoromethanesulfonic Acid SCHEMBL64156 0.73 GPR3 (0.41) GPR3KCNH2ACHEEPAS1CA1
Trifluoromethanesulfonic Acid SCHEMBL5707355 0.73 GPR3 (0.41) GPR3KCNH2ACHEEPAS1FFAR4
Trifluoromethanesulfonic Acid SCHEMBL30536254 0.72 GPR3 (0.40) GPR3KCNH2ACHEEPAS1FFAR4
SCHEMBL2778940 0.71 ALDH1A1 (0.33) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090137045-A1 Pyridinium Cationic Lipids as Gene Transfer Agents BALABAN ALEXANDRU T 2009-05-28 US disclosed
US-7456197-B2 Pyridinium cationic lipids as gene transfer agents THE TEXAS A&M UNIVERSITY SYSTEM (US) 2008-11-25 US disclosed
US-20050196863-A1 Pyridinium cationic lipids as gene transfer agents TEXAS A & M UNIVERSITY, THE 2005-09-08 US disclosed
EP-0442635-B1 Novel initiators for cationic polymerization MINNESOTA MINING & MFG (US) 1995-11-08 EP disclosed
US-5124417-A Comprising an organic onium cation and a nonnucleophilic, partially-fluorinated hydrocarbylsulfonato metallate; high-molecular-weight polymers from epoxides, tetrahydrofurans, oxazolines, vinyls, lactones, etc. MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-06-23 US disclosed
US-5084586-A Polymerization catalysts MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-01-28 US disclosed
EP-0442635-A1 Novel initiators for cationic polymerization MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-08-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050196863-A1 Pyridinium cationic lipids as gene transfer agents PTDSS2, PLIN5, PTDSS1 GPR3 2048/4885KCNH2 2138/4885ACHE 4200/4885
US-20090137045-A1 Pyridinium Cationic Lipids as Gene Transfer Agents PTDSS2, PLIN5, PTDSS1 GPR3 2048/4885KCNH2 2138/4885ACHE 4200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.