Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL64156

Cc1cc(C)[n+](F)c(C)c1.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.41
KCNH2 Q12809 9/20 0.37
ACHE P22303 5/20 0.36
CA1 P00915 3/20 0.34
CA2 P00918 3/20 0.34
CA9 Q16790 3/20 0.34
EPAS1 Q99814 1/20 0.33
CA12 O43570 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA13 Q8N1Q1 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8715817 0.85 CA2 (0.37) CA1CA2CA9CA12CA4
Trifluoromethanesulfonic Acid SCHEMBL8717967 0.85 KCNH2 (0.38) GPR3KCNH2ACHECA1CA2
Trifluoromethanesulfonic Acid SCHEMBL997394 0.82 GPR3 (0.34) GPR3KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL5571529 0.82 GPR3 (0.32) GPR3KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL4620918 0.82 ALDH1A1 (0.35) GPR3
Trifluoromethanesulfonic Acid SCHEMBL9686740 0.80 KCNH2 (0.44) GPR3KCNH2ACHE
SCHEMBL8715820 0.80 CA2 (0.34) CA1CA2CA9CA12CA4
Trifluoromethanesulfonic Acid SCHEMBL8716879 0.79 GPR3 (0.38) GPR3KCNH2ACHEEPAS1
SCHEMBL138421 0.78 ALDH1A1 (0.35) ACHE
SCHEMBL64553 0.76 LMNA (0.36) CA1CA2CA9CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 621 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025244956-A1 METHODS OF MANUFACTURING DANICAMTIV MyoKardia, Inc. (US) 2025-11-27 WO claimed
CN-119913125-A N-deoxyribotransferase II mutant and application thereof 上海合全药物研发有限公司 2025-05-02 CN claimed
CN-119790058-A Fused cyclic KRAS inhibitors for the treatment of diseases 荣山医药股份有限公司 2025-04-08 CN claimed
CN-118853142-A White light emitting material for electroluminescence and application and planar light source planar white light emitting transistor and application 中国科学院化学研究所 2024-10-29 CN claimed
US-11873289-B2 Pyrazole compounds and preparation thereof MyoKardia, Inc. (US) 2024-01-16 US claimed
CN-117120606-A Stable target editing guide RNA for introducing chemically modified nucleic acid 学校法人福冈大学 2023-11-24 CN claimed
US-20230101833-A1 CHEMICAL TREATMENT FOR PREPARING METAL ELECTRODES COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2023-03-30 US claimed
CN-115851694-A Preparation method and application of immobilized enzyme for synthesizing 2' -fluoro-deoxyribonucleoside 江苏海洋大学 2023-03-28 CN claimed
EP-4101018-A1 CHEMICAL TREATMENT FOR PREPARING METAL ELECTRODES Commonwealth Scientific and Industrial Research Organisation (AU) 2022-12-14 EP claimed
WO-2022255562-A1 SEMI-TRANSPARENT ORGANIC ELECTRONIC DEVICE INCLUDING HIGH TRANSMITTANCE AND HIGH MOBILITY COMPOSITE TRANSPARENT ELECTRODE AND MANUFACTURING METHOD THEREFOR 건국대학교 산학협력단 2022-12-08 WO claimed
EP-3426654-A1 DIRECT PALLADIUM-CATALYZED AROMATIC FLUORINATION President and Fellows of Harvard College (US) 2019-01-16 EP claimed
WO-2017156265-A1 DIRECT PALLADIUM-CATALYZED AROMATIC FLUORINATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2017-09-14 WO claimed
WO-2016087879-A1 FORMATION OF BONDS BY OUTER-SPHERE OXIDATIVE ELECTROPHILIC FLUORINATION UNIVERSITY OF YORK (GB) 2016-06-09 WO claimed
US-9024093-B2 Fluorination of organic compounds PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2015-05-05 US claimed
US-20140018566-A1 PALLADIUM(II)-CATALYZED SELECTIVE FLUORINATION OF BENZOIC ACIDS AND DERIVATIVES THE SCRIPPS RESEARCH INSTITUTE (US) 2014-01-16 US claimed
US-8558012-B2 2-fluoro-1,3-benzodithiol 1,1,3,3-tetraoxide derivative, production method thereof, and production method of monofluoromethyl group-containing compound using the same NAGOYA INSTITUTE OF TECHNOLOGY (JP) 2013-10-15 US claimed
US-20120059179-A1 PALLADIUM-CATALYZED ORTHO-FLUORINATION The Scripps Research Insitiute (US) 2012-03-08 US claimed
EP-2414317-A2 PALLADIUM-CATALYZED ORTHO-FLUORINATION The Scripps Research Institute (US) 2012-02-08 EP claimed
WO-2010115098-A2 PALLADIUM-CATALYZED ORTHO-FLUORINATION THE SCRIPPS RESEARCH INSTITUTE (US) 2010-10-07 WO claimed
WO-2009100014-A1 SYSTEM FOR FLUORINATING ORGANIC COMPOUNDS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2009-08-13 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11873289-B2 Pyrazole compounds and preparation thereof TNNI3, TNNT2, HNRNPL GPR3 2290/4885KCNH2 5/4885ACHE 4533/4885
US-20140018566-A1 PALLADIUM(II)-CATALYZED SELECTIVE FLUORINATION OF BENZOIC ACIDS AND DERIVATIVES AHR, DDT, AOC2 GPR3 890/4885KCNH2 296/4885ACHE 2451/4885
US-20120059179-A1 PALLADIUM-CATALYZED ORTHO-FLUORINATION POF1B, OCIAD2, ODC1 GPR3 2780/4885KCNH2 696/4885ACHE 1210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.