Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27323795 | 0.98 | ALDH1A1 (0.39) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL13034569 | 0.86 | ALDH1A1 (0.60) | ALDH1A1CES2CES1TP53CHRNB2 | |
| SCHEMBL3019869 | 0.83 | ALDH1A1 (0.39) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL24340744 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CES2CES1TSHRLMNA | |
| SCHEMBL26359527 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CES2CES1TSHRLMNA | |
| SCHEMBL14600035 | 0.82 | CHRNB2 (0.45) | ALDH1A1CHRNB2CHRNB4CHRNA4GAA | |
| SCHEMBL25143929 | 0.80 | CHRNB2 (0.34) | ALDH1A1CHRNB2CHRNB4CHRNA4GAA | |
| SCHEMBL25874859 | 0.79 | ALDH1A1 (0.37) | ALDH1A1CES2CES1HDAC3HDAC1 | |
| SCHEMBL740201 | 0.79 | — | — | |
| SCHEMBL16467157 | 0.79 | HSD17B10 (0.38) | ALDH1A1CHRNB2CHRNB4CHRNA4CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242565-A1 | Macrolides with Modified Desosamine Sugars and Uses Thereof | ZIKANI THERAPEUTICS, INC. | 2023-08-03 | — | — | US | disclosed |
| US-11673910-B2 | Macrolides with modified desosamine sugars and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2023-06-13 | — | — | US | disclosed |
| US-11597873-B2 | Well treatment compositions and methods comprising certain microemulsions and certain clay control additives exhibiting synergistic effect of enhancing clay swelling protection and persistency | FLOTEK CHEMISTRY, LLC (US) | 2023-03-07 | — | — | US | disclosed |
| US-20220411366-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-12-29 | — | — | US | disclosed |
| US-20220356185-A1 | MERTK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2022-11-10 | — | — | US | disclosed |
| US-11254856-B2 | Methods and compositions for use in oil and/or gas wells | FLOTEK CHEMISTRY, LLC (US) | 2022-02-22 | — | — | US | disclosed |
| US-20210371730-A1 | WELL TREATMENT COMPOSITIONS AND METHODS COMPRISING CERTAIN MICROEMULSIONS AND CERTAIN CLAY CONTROL ADDITIVES EXHIBITING SYNERGISTIC EFFECT OF ENHANCING CLAY SWELLING PROTECTION AND PERSISTENCY | FLOTEK CHEMISTRY, LLC (US) | 2021-12-02 | — | — | US | disclosed |
| US-11180690-B2 | Diluted microemulsions with low surface tensions | FLOTEK CHEMISTRY, LLC (US) | 2021-11-23 | — | — | US | disclosed |
| US-20210340435-A1 | METHODS AND COMPOSITIONS FOR STIMULATING THE PRODUCTION OF HYDROCARBONS FROM SUBTERRANEAN FORMATIONS | FLOTEK CHEMISTRY, LLC (US) | 2021-11-04 | — | — | US | disclosed |
| US-11053433-B2 | Methods and compositions for stimulating the production of hydrocarbons from subterranean formations | FLOTEK CHEMISTRY, LLC (US) | 2021-07-06 | — | — | US | disclosed |
| US-20080280871-A1 | 5-Phenyl-4-Methyl-Thiazol-2-Yl-Amine Derivatives as Inhibitors of Phosphatidylin Ositol 3 Kinase Enzymes (PI13) For Treatment of Inflammatory Diseases | NOVARTIS AG (CH) | 2008-11-13 | — | — | US | disclosed |
| US-20080015179-A1 | Modulators of muscarinic receptors | VERTEX PHARMACEUTICALS INCORPORATED | 2008-01-17 | — | — | US | disclosed |
| WO-2007112505-A1 | GLYCERIDE ESTER DERIVATIVES OF HERBICIDAL COMPOUNDS AND COMPOSITIONS THEREOF | NUFARM AUSTRALIA LIMITED (AU) | 2007-10-11 | — | — | WO | disclosed |
| US-20050064004-A1 | Surfactant/solvent mixtures | BAYER CROPSCIENCE GMBH (DE) | 2005-03-24 | — | — | US | disclosed |
| CN-1170827-C | Benzofurylpyrone derivatives | ������������ʽ���� | 2004-10-13 | — | — | CN | disclosed |
| CN-1299359-A | Benzofurylpyrone derivatives | TEIJIN LTD (JP) | 2001-06-13 | — | — | CN | disclosed |
| CN-1064045-C | Thienopyrimidine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-04-04 | — | — | CN | disclosed |
| CN-1173868-A | Thienopyrimidine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-02-18 | — | — | CN | disclosed |
| CN-1027271-C | Preparation method of n-statinib and n-cyclostatini polypeptide | PFICER CO LTD (US) | 1995-01-04 | — | — | CN | disclosed |
| CN-87101499-A | Preparation method of n-statinib and n-cyclostatini polypeptide | — | 1988-05-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11673910-B2 | Macrolides with modified desosamine sugars and uses thereof | FUT6, DDOST, MGAM | ALDH1A1 4673/4885CES2 1374/4885CES1 1142/4885 |
| US-20220411366-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | ITGB1, ITGB2, ITGA2 | ALDH1A1 399/4885CES2 1324/4885CES1 991/4885 |
| US-20080280871-A1 | 5-Phenyl-4-Methyl-Thiazol-2-Yl-Amine Derivatives as Inhibitors of Phosphatidylin Ositol 3 Kinase Enzymes (PI13) For Treatment of Inflammatory Diseases | PI4KA, IP6K3, PHOSPHO1 | ALDH1A1 4022/4885CES2 3563/4885CES1 765/4885 |
| US-20080015179-A1 | Modulators of muscarinic receptors | CHRM3, CHRM5, CHRM2 | ALDH1A1 2356/4885CES2 978/4885CES1 917/4885 |
| US-20230242565-A1 | Macrolides with Modified Desosamine Sugars and Uses Thereof | FUT6, DDOST, MGAM | ALDH1A1 4673/4885CES2 1374/4885CES1 1142/4885 |
| US-20220356185-A1 | MERTK DEGRADERS AND USES THEREOF | MERTK, ITK, CRKL | ALDH1A1 1538/4885CES2 885/4885CES1 1208/4885 |
| US-20050064004-A1 | Surfactant/solvent mixtures | C1R, C1S, HRH4 | ALDH1A1 3920/4885CES2 1195/4885CES1 640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.