Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8288650 | 0.79 | ALDH1A1 (0.68) | KMT2AALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL6996786 | 0.77 | FLT3 (0.70) | KMT2AALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL7165819 | 0.76 | MAPT (0.63) | KMT2AALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL7003777 | 0.76 | ALDH1A1 (0.62) | KMT2AALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL7005515 | 0.75 | L3MBTL1 (0.65) | KMT2AALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL7167114 | 0.75 | MAPT (0.60) | KMT2AALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL7002469 | 0.75 | ALDH1A1 (0.60) | KMT2AALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL3018829 | 0.74 | MEN1 (0.53) | KMT2AALDH1A1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL3029893 | 0.73 | MAPT (0.50) | KMT2AALDH1A1KDM4ERAB9ATP53 | |
| SCHEMBL7160571 | 0.73 | MAPT (0.55) | KMT2AALDH1A1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143411-A1 | Thiophens and Their Use as Anti-Tumor Agents | COMPASS PHARMACEUTICALS LLC (US) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143411-A1 | Thiophens and Their Use as Anti-Tumor Agents | TP53, BRDT, VHL | KMT2A 3189/4885ALDH1A1 1202/4885KDM4E 2942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.