Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Phenosafranine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.41 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.41 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.69 |
| ▸ | NPC1 | O15118 | 4/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenosafranine SCHEMBL29424348 | 1.00 | RAB9A (0.69) | RAB9ANPC1L3MBTL1NLRP3MAPT | |
| Phenosafranine SCHEMBL29588207 | 1.00 | RAB9A (0.69) | RAB9ANPC1L3MBTL1NLRP3MAPT | |
| Phenosafranine SCHEMBL3139756 | 1.00 | RAB9A (0.69) | RAB9ANPC1L3MBTL1NLRP3MAPT | |
| Phenosafranine SCHEMBL17477272 | 0.98 | RAB9A (0.68) | RAB9ANPC1L3MBTL1NLRP3MAPT | |
| Phenosafranine SCHEMBL466891 | 0.98 | RAB9A (0.68) | RAB9ANPC1L3MBTL1NLRP3MAPT | |
| SCHEMBL19052327 | 0.95 | NPC1 (0.64) | RAB9ANPC1L3MBTL1NLRP3MAPT | |
| Phenosafranine SCHEMBL11597066 | 0.92 | RAB9A (0.61) | RAB9ANPC1L3MBTL1NLRP3MAPT | |
| SCHEMBL10005184 | 0.91 | NPC1 (0.64) | RAB9ANPC1L3MBTL1NLRP3MAPT | |
| Hydrochloric Acid SCHEMBL20969348 | 0.87 | NPC1 (0.60) | RAB9ANPC1L3MBTL1NLRP3MAPT | |
| SCHEMBL20554944 | 0.87 | NPC1 (0.60) | RAB9ANPC1L3MBTL1NLRP3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1797 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026088160-A1 | IMPROVED ELECTROCHEMICAL BIOSENSORS | ARMA BIOSCIENCES (CA) | 2026-04-30 | — | — | WO | claimed |
| US-12605484-B2 | Two-component system for the therapeutic treatment of skin lesions and production method thereof | DTECH - SOCIETÀ A RESPONSABILITÀ LIMITATA (IT) | 2026-04-21 | — | — | US | claimed |
| US-20250339812-A1 | ELECTROCHEMICAL DIRECT AIR CAPTURE OF CARBON DIOXIDE USING REVERSIBLE REDOX-ACTIVE MATERIAL | MASSACHUSETTS INST TECHNOLOGY (US) | 2025-11-06 | — | — | US | claimed |
| EP-4551936-A1 | A METHOD OF DETECTING AN ANALYTE IN A SAMPLE AND A BIOSENSOR, A METHOD OF PRODUCING THE BIOSENSOR AND AN ELECTROCHEMICAL SENSOR SYSTEM COMPRISING THE BIOSENSOR | Solsten Diagnostics International ApS (DK) | 2025-05-14 | — | — | EP | claimed |
| WO-2024249876-A2 | BIOSENSOR BASED ON A NEAR FIELD COMMUNICATION USING DIRECT ELECTRON TRANSFER | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2024-12-05 | — | — | WO | claimed |
| WO-2024233595-A1 | LIGHT ACTIVATED CLEANING COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2024-11-14 | — | — | WO | claimed |
| US-20240374769-A1 | LIGHT ACTIVATED CLEANING COMPOSITION | THE PROCTER & GAMBLE COMPANY | 2024-11-14 | — | — | US | claimed |
| EP-4324509-A2 | WOUND DRESSINGS AND SYSTEMS WITH THERAPEUTIC GAS AND NEGATIVE PRESSURE SOURCES FOR INCISION MANAGEMENT AND RELATED METHODS | 3M Innovative Properties Company (US) | 2024-02-21 | — | — | EP | claimed |
| EP-4076733-B1 | PEROVSKITE SOLAR CELL PROVIDED WITH AN ADSORBENT MATERIAL FOR ADSORBING TOXIC MATERIALS | ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) | 2024-02-07 | — | — | EP | claimed |
| WO-2024008260-A1 | A METHOD OF DETECTING AN ANALYTE IN A SAMPLE AND A BIOSENSOR, A METHOD OF PRODUCING THE BIOSENSOR AND AN ELECTROCHEMICAL SENSOR SYSTEM COMPRISING THE BIOSENSOR | SOLSTEN DIAGNOSTICS INTERNATIONAL APS (DK) | 2024-01-11 | — | — | WO | claimed |
| US-4345470-A | All plastic disposable thermometer | AKZONA INCORPORATED (US) | 1982-08-24 | — | — | US | claimed |
| US-4299727-A | Disposable reversible thermometer | AKZONA INCORPORATED (US) | 1981-11-10 | — | — | US | claimed |
| US-4232552-A | THERMOCHROMISM, DISPOSABLE THERMOMETERS | AKZONA INCORPORATED (US) | 1980-11-11 | — | — | US | claimed |
| US-4177071-A | HIGH SENSITIVITY TO PENTRATING RADIATION; INSENSITIVE TO FORMATION OF PRESSURE MARKS | AGFA-GEVAERT, N.V. (BE) | 1979-12-04 | — | — | US | claimed |
| US-4169811-A | DYE, ALKYLINE MATERIAL, REDUCING AGENT | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 1979-10-02 | — | — | US | claimed |
| US-4113490-A | DEVELOPMENT, AMPLIFYING BATH CONTAINING HYDROGEN PEROXIDE | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1978-09-12 | — | — | US | claimed |
| US-4094682-A | Method for processing light-sensitive silver halide photographic material | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) | 1978-06-13 | — | — | US | claimed |
| US-4057819-A | Semiconductor device | OWEN ALAN ERNEST | 1977-11-08 | — | — | US | claimed |
| US-4011081-A | DIRECT-POSITIVE DOUBLE EXPOSURE PROCESS UTILIZING A PRIMITIVE, UNFOGGED SILVER HALIDE EMULSION CONTAINING AN ELECTRON ACCEPTOR | EASTMAN KODAK COMPANY (US) | 1977-03-08 | — | — | US | claimed |
| US-3970459-A | Process for developing a direct reversal silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JA) | 1976-07-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12605484-B2 | Two-component system for the therapeutic treatment of skin lesions and production method thereof | CUTA, CA2, ORAI1 | CHRM2 1399/4885ACHE 2189/4885SLC6A2 2545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.