Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2444862 | 0.82 | PKM (0.39) | TDP1OPRD1GAA | |
| SCHEMBL339944 | 0.77 | KDM4E (0.43) | TDP1PTGDR2 | |
| SCHEMBL342177 | 0.76 | MAPT (0.43) | TDP1OPRD1GAA | |
| SCHEMBL2979449 | 0.72 | MAPT (0.42) | TDP1GAA | |
| SCHEMBL7640011 | 0.70 | MAPT (0.47) | TDP1OPRD1GAA | |
| SCHEMBL28401713 | 0.69 | LMNA (0.42) | TDP1OPRD1PTGDR2 | |
| SCHEMBL17584752 | 0.68 | ALDH1A1 (0.41) | TDP1 | |
| SCHEMBL1358303 | 0.67 | MAPT (0.41) | TDP1PTGDR2 | |
| SCHEMBL6051256 | 0.66 | LMNA (0.44) | TDP1GAA | |
| SCHEMBL341877 | 0.65 | HTT (0.38) | TDP1GAAPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137393-A1 | 2,4,6-TRIALKYLPHENYL SUBSTITUTED CYCLOPENTANE-1,3-DIONE | BAYER CROPSCIENCE AG (DE) | 2009-05-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137393-A1 | 2,4,6-TRIALKYLPHENYL SUBSTITUTED CYCLOPENTANE-1,3-DIONE | DDT, CYP1B1, CNPY2 | TDP1 363/4885OPRD1 1891/4885GAA 1828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.